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| Status |
Public on Aug 29, 2018 |
| Title |
Expression data in non-tumor liver tissues from Peruvian patients with hepatocellular carcinoma. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Most hepatocellular carcinomas in younger patients from Peru arise from non-cirrhotic livers. Histological examination of the non-tumor liver tissues highlights the presence of clear cell foci in a significant fraction of Peruvian patients with hepatocellular carcinoma.
We used microarrays to compare gene expression between non-tumor liver tissues with and without clear cell foci and identified ontologies that are distinctively differentially expressed between subsets.
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| Overall design |
Non-tumor liver tissues were obtained from tumour-free margins of resected surgical pieces. Total RNA was isolated from flash-frozen samples for hybridization on Affymetrix microarrays. We selected non-tumour liver tissues according to the presence or the absence of clear cell foci in non-tumor liver parenchyma in formalin-fixed, paraffin-embedded counterpart samples under haematoxylin–eosin staining.
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| Contributor(s) |
Cerapio JP, Pineau P |
| Citation(s) |
30061721, 33747361 |
| Submission date |
Mar 08, 2018 |
| Last update date |
Mar 23, 2021 |
| Contact name |
Juan Pablo Cerapio |
| E-mail(s) |
jcerapioarroyo@gmail.com, juan-pablo.cerapio-arroyo@inserm.fr
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| Organization name |
CRCT
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| Street address |
Av 2 Hubert Curien
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| City |
Toulouse |
| ZIP/Postal code |
31000 |
| Country |
France |
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| Platforms (1) |
| GPL17586 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
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| Samples (9)
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| Relations |
| BioProject |
PRJNA437461 |
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