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Series GSE113025 Query DataSets for GSE113025
Status Public on Jul 30, 2019
Title Histone Recycling by FACT and Spt6 during Transcription Prevents the Scrambling of Histone Modifications [tiling]
Organism Saccharomyces cerevisiae
Experiment type Genome binding/occupancy profiling by genome tiling array
Summary The genetic information encoded in DNA is framed by additional layers of information, referred to as the epigenome. Epigenetic marks such as DNA methylation, histone modifications and histone variants are concentrated on specific genomic sites as means to instruct, but also sometimes as a consequence of, gene expression. How this information is maintained, notably in the face of transcription, is not understood. Here we show that the histone chaperones FACT and Spt6 are required for maintaining proper localization of several histone modifications including H3K4me1,2,3, H3K36me3, H3K79me3, H3K14ac, H3K18ac and H2Bub in Saccharomyces cerevisiae. In the absence of functional FACT or Spt6, transcription generates massive nucleosome loss which is partially compensated by increased histone assembly by histone chaperones such as Asf1 and HIR. Because re-incorporation of histones by these histone chaperones in not coupled to transcription, the modified histones are randomly incorporated, leading to scrambling of the epigenetic information. Hence, our work highlights the importance of local nucleosome recycling by FACT and Spt6 during transcription in the maintenance of a proper epigenetic landscape.
 
Overall design We profiled eight histone modifications in temperature-sensitive mutants for the histone chaperones FACT and Spt6 (spt16-197 and spt6-1004 respectively) in yeast Saccharomyces cerevisiae by ChIP-chip on tiling arrays. These histone modifications included H3K4me1, H3K4me2, H3K4me3, H3K36me3, H3K79me3, H3K14ac, H3K18ac and H2Bub. Abrogating the function of FACT or Spt6 leads to redistribution of the modified histones. The contribution of FACT and Spt6 on H3K4me3 mislocalization was also confirmed by nuclear depletion of Spt16 and Spt6 using the anchor-away system. In addition, we profiled histones (H4, H3, H2B) and RNAPII occupancy in wild type, spt16-197 and spt6-1004 cells. RNAPII occupancy was also measured in a temperature-sensitive mutant for RNAPII (rpb1-1). In order to investigate whether nucleosome loss may lead to mislocalization of histone modifications, we profiled H4, RNAPII, FACT and histone modifications in cells where H4 expression was shutdown using a system developed by the Grunstein lab (Han and Grunstein, 1988). To test if the chromatin defects observed in the FACT and Spt6 mutants are caused by transcription, we inhibited transcription (or not) by treating cells with thiolutin, concomitantly to anchoring-away FACT or Spt6, and performed H3K4me3, H3K36me3, H4 and RNAPII ChIP-chip experiments. In addition, H3K4me3 ChIP-chip experiments were performed in htz1Δ, spt16-197/htz1Δ and spt6-1004/htz1Δ cells in order to rule out that the defects in histone modifications may occur because of the histone variant H2A.Z mislocalization in FACT and Spt6 mutants. H3K4me3 occupancy was also measured in ATP-dependent chromatin remodeler mutants including chd1Δ, spt16-197/chd1Δ, isw1Δ, spt16-197/isw1Δ, isw2Δ, spt16-197/isw2Δ. Finally, the localization of the histone chaperones Asf1 and HIR (FLAG –tagged) was determined in wild type and in spt16-197 cells. All ChIP samples were labeled with Cy5 and hybridized against appropriate samples that range from Input DNA, H2B, H3, H4 or NoTag ChIP samples (labeled with Cy3). The microarrays used were described before (Jeronimo and Robert, 2014). The data were normalized by setting the median of log2 ratios to zero. Each experiment was done in duplicate.
 
Contributor(s) Jeronimo C, Poitras C, Robert F
Citation(s) 31365865
Submission date Apr 11, 2018
Last update date Oct 29, 2019
Contact name Francois Robert
E-mail(s) francois.robert@ircm.qc.ca
Organization name IRCM
Lab Chromatin and Genomic Expression
Street address 110 av des Pins Ouest
City Montreal
State/province QC
ZIP/Postal code H2W 1R7
Country Canada
 
Platforms (2)
GPL18340 Agilent-034462 Yeast_4x180K
GPL24876 Agilent-034462 Yeast_4x180K [PROBE NAME]
Samples (280)
GSM3093884 yFR971_WT_80min37C_H3vsInput_20150721_Rep1
GSM3093885 yFR971_WT_80min37C_H3vsInput_20150721_Rep2
GSM3093886 yFR973_spt16-197_80min37C_H3vsInput_20150721_Rep1
This SubSeries is part of SuperSeries:
GSE113270 Histone Recycling by FACT and Spt6 during Transcription Prevents the Scrambling of Histone Modifications
Relations
BioProject PRJNA449917

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SOFT formatted family file(s) SOFTHelp
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Supplementary file Size Download File type/resource
GSE113025_Jan2019_NewSamples_median_norm_log2_ratios.xlsx 40.3 Mb (ftp)(http) XLSX
GSE113025_RAW.tar 12.3 Gb (http)(custom) TAR (of GPR)
GSE113025_SmthBED_yFR116-WT_H3K4me3vsInput_20190416_rep1-2_S.cerevisiaeApr11_933835.bed.gz 8.7 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR116_Thiolutin_Rpb3vsInput_SPIKE-IN_Rep1-2__S.cerevisiaeApr11_873611.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR116_WT_Rpb3vsInput_SPIKE-IN_Rep1-2__S.cerevisiaeApr11_861328.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1214_rpb1-1_80min37C_Rpb3vsInput_20170621_Rep1-2_MN__S.cerevisiaeApr11_849357.bed.gz 8.3 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1221_WT_80min37C_Rpb3vsInput_20170621_Rep1-2_MN__S.cerevisiaeApr11_621451.bed.gz 8.4 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1222_htz1D_H3K4me3vsH4_SPIKE-IN_Rep1-2_MN__S.cerevisiaeApr11_880938.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1240_WT-RNAPII_H3K4me3vsInput_20171012_rep1-2_MN__S.cerevisiaeApr11_400555.bed.gz 8.7 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1242_H1085Ymutant-SlowRNAPII_H3K4me3vsInput_20171012_rep1-2_MN__S.cerevisiaeApr11_985929.bed.gz 8.7 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1252_G1097Dmutant-FastRNAPII_H3K4me3vsInput_20171012_rep1-2_MN__S.cerevisiaeApr11_651604.bed.gz 8.7 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1321_WT_90minRap_H3K4me3vsInput_rep1-2_MN__S.cerevisiaeApr11_965735.bed.gz 8.7 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1416_spt16-197-htz1D_H3K4me3vsH4_SPIKE-IN_Rep1-2_MN__S.cerevisiaeApr11_171031.bed.gz 8.3 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1420_spt6-1004-htz1D_H3K4me3vsH4_SPIKE-IN_Rep1-2_MN__S.cerevisiaeApr11_695465.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1478_Spt16-AA_90minRap_H3K4me3vsInput_rep1-2_MN__S.cerevisiaeApr11_852796.bed.gz 8.4 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1478_Spt16-AA_DMSO_H3K36me3vsInput_20170712_Rep1-2__S.cerevisiaeApr11_228628.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1478_Spt16-AA_DMSO_H3K4me3vsInput_20170630_Rep1-2__S.cerevisiaeApr11_652015.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1478_Spt16-AA_DMSO_H4vsInput_20170712_Rep1-2__S.cerevisiaeApr11_453288.bed.gz 8.2 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1478_Spt16-AA_DMSO_Rpb3vsInput_20170630_Rep1-2__S.cerevisiaeApr11_406219.bed.gz 8.4 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1478_Spt16-AA_Rapa30min_H3K36me3vsInput_20170712_Rep1-2__S.cerevisiaeApr11_554337.bed.gz 8.3 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1478_Spt16-AA_Rapa30min_H3K4me3vsInput_20170630_Rep1-2__S.cerevisiaeApr11_230872.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1478_Spt16-AA_Rapa30min_H4vsInput_20170712_Rep1-2__S.cerevisiaeApr11_994637.bed.gz 8.3 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1478_Spt16-AA_Rapa30min_Rpb3vsInput_20170630_Rep1-2__S.cerevisiaeApr11_806958.bed.gz 8.3 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1478_Spt16-AA_Thio-Rapa30min_H3K36me3vsInput_20170712_Rep1-2__S.cerevisiaeApr11_279110.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1478_Spt16-AA_Thio-Rapa30min_H3K4me3vsInput_20170630_Rep1-2__S.cerevisiaeApr11_442855.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1478_Spt16-AA_Thio-Rapa30min_H4vsInput_20170712_Rep1-2__S.cerevisiaeApr11_406766.bed.gz 8.3 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1478_Spt16-AA_Thio-Rapa30min_Rpb3vsInput_20170630_Rep1-2__S.cerevisiaeApr11_950859.bed.gz 8.4 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1480_Spt6-AA_90minRap_H3K4me3vsInput_rep1-2_MN__S.cerevisiaeApr11_419766.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1480_Spt6-AA_DMSO_H3K36me3vsInput_20171031_rep1-2__S.cerevisiaeApr11_488797.bed.gz 8.7 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1480_Spt6-AA_DMSO_H3K4me3vsInput_20171031_rep1-2__S.cerevisiaeApr11_245913.bed.gz 8.7 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1480_Spt6-AA_DMSO_H4vsInput_20171031_rep1-2__S.cerevisiaeApr11_523077.bed.gz 8.3 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1480_Spt6-AA_DMSO_Rpb3vsInput_20171031_rep1-2__S.cerevisiaeApr11_412782.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1480_Spt6-AA_Rapa30min_H3K36me3vsInput_20171031_rep1-2__S.cerevisiaeApr11_507349.bed.gz 8.7 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1480_Spt6-AA_Rapa30min_H3K4me3vsInput_20171031_rep1-2__S.cerevisiaeApr11_740872.bed.gz 8.7 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1480_Spt6-AA_Rapa30min_H4vsInput_20171031_rep1-2__S.cerevisiaeApr11_121003.bed.gz 8.4 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1480_Spt6-AA_Rapa30min_Rpb3vsInput_20171031_rep1-2__S.cerevisiaeApr11_395386.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1480_Spt6-AA_Thio-Rapa30min_H3K36me3vsInput_20171031_rep1-2__S.cerevisiaeApr11_685567.bed.gz 8.7 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1480_Spt6-AA_Thio-Rapa30min_H3K4me3vsInput_20171031_rep1-2__S.cerevisiaeApr11_204637.bed.gz 8.7 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1480_Spt6-AA_Thio-Rapa30min_H4vsInput_20171031_rep1-2__S.cerevisiaeApr11_983073.bed.gz 8.4 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1480_Spt6-AA_Thio-Rapa30min_Rpb3vsInput_20171031_rep1-2__S.cerevisiaeApr11_737165.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1558_chd1D_80min37C_H3K4me3vsInput_20170927_FB_MN_rep1-2__S.cerevisiaeApr11_273310.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1562_spt16-197_chd1D_80min37C_H3K4me3vsInput_20170927_FB_MN_rep1-2__S.cerevisiaeApr11_584807.bed.gz 8.4 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1580_isw1D_80min37C_H3K4me3vsInput_20170927_FB_MN_rep1-2__S.cerevisiaeApr11_820085.bed.gz 8.7 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1584_spt16-197_isw1D_80min37C_H3K4me3vsInput_20170927_FB_MN_rep1-2__S.cerevisiaeApr11_643363.bed.gz 8.4 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1588_isw2D_80min37C_H3K4me3vsInput_20170927_FB_MN_rep1-2__S.cerevisiaeApr11_51978.bed.gz 8.2 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR1592_spt16-197_isw2D_80min37C_H3K4me3vsInput_20170927_FB_MN_rep1-2__S.cerevisiaeApr11_87027.bed.gz 8.3 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR2113_pGAL1-H4_6hrs-YEP-Glucose_H4vsInput_20161121_rep1-2_MN__S.cerevisiaeApr11_323220.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR2113_pGAL1-H4_6hrs-YPD_H2BubvsInput_20161130_rep1-2_MN__S.cerevisiaeApr11_350238.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR2113_pGAL1-H4_6hrs-YPD_H3K18acvsInput_20161201_rep1-2_MN__S.cerevisiaeApr11_731439.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR2113_pGAL1-H4_6hrs-YPD_H3K36me3vsInput_20161201_rep1-2_MN__S.cerevisiaeApr11_911918.bed.gz 8.7 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR2113_pGAL1-H4_6hrs-YPD_H3K4me1vsInput_20161130_rep1-2_MN__S.cerevisiaeApr11_948688.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR2113_pGAL1-H4_6hrs-YPD_H3K4me2vsInput_20161130_rep1-2_MN__S.cerevisiaeApr11_266135.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR2113_pGAL1-H4_6hrs-YPD_H3K79me3vsInput_20161201_rep1-2_MN__S.cerevisiaeApr11_34841.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR2113_pGAL1-H4_H3K4me3vsInput_6hrsYPD_20160703_rep1-2_MN__S.cerevisiaeApr11_287568.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR2113_pGAL1-H4_Rpb3vsInput_6hrsYPD_20160703_rep1-2_MN__S.cerevisiaeApr11_921419.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR2113_pGAL1-H4_Spt16vsInput_6hrsYPD_20160703_rep1-2_MN__S.cerevisiaeApr11_468341.bed.gz 8.3 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR2114_WT_6hrs-YEP-Glucose_H4vsInput_20161121_rep1-2_MN__S.cerevisiaeApr11_714650.bed.gz 8.3 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR2114_WT_6hrs-YPD_H2BubvsInput_20161130_rep1-2_MN__S.cerevisiaeApr11_885856.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR2114_WT_6hrs-YPD_H3K18acvsInput_20161201_rep1-2_MN__S.cerevisiaeApr11_947320.bed.gz 8.7 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR2114_WT_6hrs-YPD_H3K36me3vsInput_20161201_rep1-2_MN__S.cerevisiaeApr11_335447.bed.gz 8.7 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR2114_WT_6hrs-YPD_H3K4me1vsInput_20161130_rep1-2_MN__S.cerevisiaeApr11_767758.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR2114_WT_6hrs-YPD_H3K4me2vsInput_20161130_rep1-2_MN__S.cerevisiaeApr11_569757.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR2114_WT_6hrs-YPD_H3K79me3vsInput_20161201_rep1-2_MN__S.cerevisiaeApr11_594932.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR2114_WT_H3K4me3vsInput_6hrsYPD_20160703_rep1-2_MN__S.cerevisiaeApr11_100233.bed.gz 8.7 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR2114_WT_Rpb3vsInput_6hrsYPD_20160703_rep1-2_MN__S.cerevisiaeApr11_556636.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR2114_WT_Spt16vsInput_6hrsYPD_20160703_rep1-2_MN__S.cerevisiaeApr11_200941.bed.gz 8.4 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR2995vs971_Asf1-3FLAGvsNoTag_WT_20171203_Rep1-2_MN__S.cerevisiaeApr11_971324.bed.gz 8.4 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR2997vs973_Asf1-3FLAGvsNoTag_spt16-197_20171203_Rep1-2_MN__S.cerevisiaeApr11_556058.bed.gz 8.3 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR3000vs971_Hir1-3FLAGvsNoTag_WT_20171203_Rep1-2_MN__S.cerevisiaeApr11_729188.bed.gz 8.3 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR3002vs973_Hir1-3FLAGvsNoTag_spt16-197_20171203_Rep1-2_MN__S.cerevisiaeApr11_167062.bed.gz 8.3 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR3143_WT_IAA60min_Rapa30min_H3K4me3vsInput_20180924_rep1-2__S.cerevisiaeApr11_759661.bed.gz 8.7 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR3147_SWD1-AID_IAA60min_Rapa30min_H3K4me3vsInput_20180924_rep1-2__S.cerevisiaeApr11_206111.bed.gz 8.7 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR3149_Spt16-FRB_IAA60min_Rapa30min_H3K4me3vsInput_20180924_rep1-2__S.cerevisiaeApr11_356014.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR3150_SWD1-AID_SPT16-FRB_IAA60min_Rapa30min_H3K4me3vsInput_20180924_rep1-2__S.cerevisiaeApr11_511173.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR348-set2D_H3K4me3vsInput_20190416_rep1-2_S.cerevisiaeApr11_848395.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR772-rco1D_H3K4me3vsInput_20190416_rep1-2_S.cerevisiaeApr11_637710.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR927-isw1D_H3K4me3vsInput_20190416_rep1-2_S.cerevisiaeApr11_197426.bed.gz 8.7 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR930-chd1D_H3K4me3vsInput_20190416_rep1-2_S.cerevisiaeApr11_379531.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR971_SPT16-WT_80min37C_H2BubvsH2B_20161107_Rep1-2_MN__S.cerevisiaeApr11_57600.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR971_SPT16-WT_80min37C_H2BvsInput_20170608_Rep1-2_MN__S.cerevisiaeApr11_550143.bed.gz 8.3 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR971_SPT16-WT_80min37C_H3K14ac-H4_20161102_Rep1-2_MN__S.cerevisiaeApr11_914550.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR971_SPT16-WT_80min37C_H3K14acvsInput_20170530_Rep1-2_MN__S.cerevisiaeApr11_98488.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR971_SPT16-WT_80min37C_H3K18ac-H4_20161102_Rep1-2_MN__S.cerevisiaeApr11_239781.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR971_SPT16-WT_80min37C_H3K18acvsInput_20170530_Rep1-2_MN__S.cerevisiaeApr11_819388.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR971_SPT16-WT_80min37C_H3K36me3vsH4_20150323_Rep1-2_MN__S.cerevisiaeApr11_723783.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR971_SPT16-WT_80min37C_H3K36me3vsInput_20170621_Rep1-2_MN__S.cerevisiaeApr11_101668.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR971_SPT16-WT_80min37C_H3K4me1vsH4_20161024_Rep1-2_MN__S.cerevisiaeApr11_937479.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR971_SPT16-WT_80min37C_H3K4me1vsInput_20170607_Rep1-2_MN__S.cerevisiaeApr11_101001.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR971_SPT16-WT_80min37C_H3K4me2vsH4_20161024_Rep1-2_MN__S.cerevisiaeApr11_731901.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR971_SPT16-WT_80min37C_H3K4me2vsInput_20170607_Rep1-2_MN__S.cerevisiaeApr11_337301.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR971_SPT16-WT_80min37C_H3K4me3vsInput_20150409_rep1-2_MN__S.cerevisiaeApr11_315468.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR971_SPT16-WT_80min37C_H3K79me3vsH4_20150323_Rep1-2_MN__S.cerevisiaeApr11_125646.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR971_SPT16-WT_80min37C_H3K79me3vsInput_20170621_Rep1-2MN__S.cerevisiaeApr11_971448.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR971_SPT16-WT_80min37C_ubH2BvsInput_20170608_Rep1-2_MN__S.cerevisiaeApr11_944786.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR971_WT-SPT16_H3K4me3vsMock_20150409_rep1-2_MN__S.cerevisiaeApr11_832620.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR971_WT_80min37C_H3K4me3vsInput_20170927_FB_MN_rep1-2__S.cerevisiaeApr11_501555.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR971_WT_80min37C_H3k4me3vsH3_20150718_Rep1-2_MN__S.cerevisiaeApr11_961606.bed.gz 8.7 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR971_WT_80min37C_H3vsInput_20150721_Rep1-2_MN__S.cerevisiaeApr11_588993.bed.gz 8.4 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR971_WT_H3K4me3vsH4_SPIKE-IN_Rep1-2_MN__S.cerevisiaeApr11_765232.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR971_WT_Rpb3_Rep1-2_MN__S.cerevisiaeApr11_30665.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR973_spt16-197_80min37C_H2BubvsH2B_20161107_Rep1-2_MN__S.cerevisiaeApr11_714622.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR973_spt16-197_80min37C_H2BvsInput_20170608_Rep1-2_MN__S.cerevisiaeApr11_861354.bed.gz 8.3 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR973_spt16-197_80min37C_H3K14ac-H4_20161102_Rep1-2_MN__S.cerevisiaeApr11_499915.bed.gz 8.3 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR973_spt16-197_80min37C_H3K14acvsInput_20170530_Rep1-2_MN__S.cerevisiaeApr11_559617.bed.gz 8.4 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR973_spt16-197_80min37C_H3K18ac-H4_20161102_Rep1-2_MN__S.cerevisiaeApr11_401897.bed.gz 8.4 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR973_spt16-197_80min37C_H3K18acvsInput_20170530_Rep1-2_MN__S.cerevisiaeApr11_78813.bed.gz 8.3 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR973_spt16-197_80min37C_H3K36me3vsH4_20150323_Rep1-2_MN__S.cerevisiaeApr11_268761.bed.gz 8.3 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR973_spt16-197_80min37C_H3K36me3vsInput_20170621_Rep1-2_MN__S.cerevisiaeApr11_74391.bed.gz 8.4 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR973_spt16-197_80min37C_H3K4me1vsH4_20161024_Rep1-2_MN__S.cerevisiaeApr11_404809.bed.gz 8.2 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR973_spt16-197_80min37C_H3K4me1vsInput_20170607_Rep1-2_MN__S.cerevisiaeApr11_758499.bed.gz 8.4 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR973_spt16-197_80min37C_H3K4me2vsH4_20161024_Rep1-2_MN__S.cerevisiaeApr11_202708.bed.gz 8.2 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR973_spt16-197_80min37C_H3K4me2vsInput_20170607_Rep1-2_MN__S.cerevisiaeApr11_574294.bed.gz 8.4 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR973_spt16-197_80min37C_H3K4me3vsInput_20150409_rep1-2_MN__S.cerevisiaeApr11_484236.bed.gz 8.4 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR973_spt16-197_80min37C_H3K4me3vsInput_20170927_FB_MN_rep1-2__S.cerevisiaeApr11_48113.bed.gz 8.4 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR973_spt16-197_80min37C_H3K79me3vsH4_20150323_Rep1-2_MN__S.cerevisiaeApr11_881807.bed.gz 8.2 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR973_spt16-197_80min37C_H3K79me3vsInput_20170621_Rep1-2_MN__S.cerevisiaeApr11_693338.bed.gz 8.4 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR973_spt16-197_80min37C_H3k4me3vsH3_20150718_Rep1-2_MN__S.cerevisiaeApr11_907267.bed.gz 8.3 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR973_spt16-197_80min37C_H3vsInput_20150721_Rep1-2_MN__S.cerevisiaeApr11_196984.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR973_spt16-197_80min37C_ubH2BvsInput_20170608_Rep1-2_MN__S.cerevisiaeApr11_33826.bed.gz 8.4 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR973_spt16-197_H3K4me3vsH4_SPIKE-IN_Rep1-2_MN__S.cerevisiaeApr11_775521.bed.gz 8.3 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR973_spt16-197_H3K4me3vsMock_20150409_rep1-2_MN__S.cerevisiaeApr11_732941.bed.gz 8.3 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR973_spt16ts_Rpb3_Rep1-2_MN__S.cerevisiaeApr11_452825.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR974_spt6-1004_80min37C_H2BubvsH2B_20161107_Rep1-2_MN__S.cerevisiaeApr11_954906.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR974_spt6-1004_80min37C_H2BvsInput_20170608_Rep1-2_MN__S.cerevisiaeApr11_329608.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR974_spt6-1004_80min37C_H3K14ac-H4_20161102_Rep1-2_MN__S.cerevisiaeApr11_162318.bed.gz 8.3 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR974_spt6-1004_80min37C_H3K14acvsInput_20170530_Rep1-2_MN__S.cerevisiaeApr11_129089.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR974_spt6-1004_80min37C_H3K18ac-H4_20161102_Rep1-2_MN__S.cerevisiaeApr11_708393.bed.gz 8.4 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR974_spt6-1004_80min37C_H3K18acvsInput_20170530_Rep1-2_MN__S.cerevisiaeApr11_165064.bed.gz 8.4 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR974_spt6-1004_80min37C_H3K4me1vsH4_20161024_Rep1-2_MN__S.cerevisiaeApr11_899330.bed.gz 8.3 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR974_spt6-1004_80min37C_H3K4me1vsInput_20170607_Rep1-2_MN__S.cerevisiaeApr11_967072.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR974_spt6-1004_80min37C_H3K4me2vsH4_20161024_Rep1-2_MN__S.cerevisiaeApr11_953374.bed.gz 8.3 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR974_spt6-1004_80min37C_H3K4me2vsInput_20170607_Rep1-2_MN__S.cerevisiaeApr11_422765.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR974_spt6-1004_80min37C_H3K4me3vsInput_20150409_rep1-2_MN__S.cerevisiaeApr11_966931.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR974_spt6-1004_80min37C_H3K79me3vsH4_20150323_Rep1-2_MN__S.cerevisiaeApr11_421990.bed.gz 8.4 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR974_spt6-1004_80min37C_H3K79me3vsInput_20170621_Rep1-2_MN__S.cerevisiaeApr11_53208.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR974_spt6-1004_80min37C_H3k4me3vsH3_20150718_Rep1-2_MN__S.cerevisiaeApr11_570936.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR974_spt6-1004_80min37C_H3vsInput_20150721_Rep1-2_MN__S.cerevisiaeApr11_507920.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR974_spt6-1004_80min37C_ubH2BvsInput_20170608_Rep1-2_MN__S.cerevisiaeApr11_841929.bed.gz 8.6 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR974_spt6-1004_H3K4me3vsH4_Rep1-2_MN__S.cerevisiaeApr11_130755.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR974_spt6-1004_H3K4me3vsH4_SPIKE-IN_Rep1-2_MN__S.cerevisiaeApr11_357403.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR974_spt6-1004_H3K4me3vsMock_20150409_rep1-2_MN__S.cerevisiaeApr11_412362.bed.gz 8.5 Mb (ftp)(http) BED
GSE113025_SmthBED_yFR974_spt6ts_Rpb3_Rep1-2_MN__S.cerevisiaeApr11_961223.bed.gz 8.5 Mb (ftp)(http) BED
Processed data are available on Series record
Processed data included within Sample table
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