|
| Status |
Public on Jun 24, 2019 |
| Title |
Selective Targeting of PARP2 Inhibits Androgen Receptor Signaling and Prostate Cancer Growth Through Disruption of FOXA1 Function |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
This SuperSeries is composed of the SubSeries listed below.
|
| |
|
| Overall design |
Refer to individual Series
|
| Web link |
https://www.pnas.org/content/early/2019/07/01/1908547116.short?rss=1
|
| |
|
| Contributor(s) |
Gui B, Jia L |
| Citation(s) |
31266892 |
| |
| Submission date |
May 10, 2018 |
| Last update date |
Jul 09, 2019 |
| Contact name |
Li Jia |
| E-mail(s) |
ljia@bwh.harvard.edu
|
| Organization name |
Brigham and Women's Hospital
|
| Department |
Surgery
|
| Lab |
Thorn 1529
|
| Street address |
20 Shattuck Street
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02115 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
| Samples (31)
|
|
| This SuperSeries is composed of the following SubSeries: |
| GSE114273 |
Gene expression profilings for prostate cancer cells after inhibition of PARP1 or PARP2 using pharmaceutical or siRNA-based approaches |
| GSE114274 |
Genome-wide occupation of AR, FOXA1, and H3K27AC in LNCaP cells treated with selective PARP2 inhibitor UPF-1069 |
|
| Relations |
| BioProject |
PRJNA470767 |
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