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GEO help: Mouse over screen elements for information. |
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Status |
Public on Jul 25, 2009 |
Title |
Expression data from LNCaP and abl cells |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Androgen receptor (AR) is a ligand-dependent transcription factor that plays a key role in the onset and progression of prostate cancer. We investigated AR-induced gene expression in prostate cancer cells LNCaP and abl by transfecting siAR / siControl or treating cells with androgen (DHT) over a time course. Keywords: siRNA transfection and androgen stimulation time course
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Overall design |
We hybridized RNA to Affymetrix human genome U133 plus 2.0 arrays.
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Contributor(s) |
Wang Q, Brown M |
Citation(s) |
19632176 |
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Submission date |
May 13, 2008 |
Last update date |
Mar 25, 2019 |
Contact name |
Arjun Kumar Manrai |
E-mail(s) |
manrai@post.harvard.edu
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Organization name |
Dana Farber Cancer Institute
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Department |
Department of Biostatistics and Computational Biology
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Lab |
X. Shirley Liu
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Street address |
44 Binney Street, Mail Stop LW225
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City |
Boston |
State/province |
MA |
ZIP/Postal code |
02115 |
Country |
USA |
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Platforms (1) |
GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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Samples (21)
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GSM288293 |
LNCaP siControl, biological replicate 1 |
GSM288294 |
LNCaP siControl, biological replicate 2 |
GSM288295 |
LNCaP siControl, biological replicate 3 |
GSM288296 |
abl siControl, biological replicate 1 |
GSM288297 |
abl siControl, biological replicate 2 |
GSM288298 |
abl siControl, biological replicate 3 |
GSM288299 |
LNCaP siAR, biological replicate 1 |
GSM288300 |
LNCaP siAR, biological replicate 2 |
GSM288301 |
LNCaP siAR, biological replicate 3 |
GSM288302 |
abl siAR, biological replicate 1 |
GSM288303 |
abl siAR, biological replicate 2 |
GSM288304 |
abl siAR, biological replicate 3 |
GSM288305 |
abl vehicle, biological replicate 1 |
GSM288306 |
abl vehicle, biological replicate 2 |
GSM288307 |
abl vehicle, biological replicate 3 |
GSM288308 |
abl DHT 4hr, biological replicate 1 |
GSM288309 |
abl DHT 4hr, biological replicate 2 |
GSM288310 |
abl DHT 4hr, biological replicate 3 |
GSM288311 |
abl DHT 16hr, biological replicate 1 |
GSM288312 |
abl DHT 16hr, biological replicate 2 |
GSM288313 |
abl DHT 16hr, biological replicate 3 |
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Relations |
BioProject |
PRJNA106451 |
Supplementary file |
Size |
Download |
File type/resource |
GSE11428_RAW.tar |
95.9 Mb |
(http)(custom) |
TAR (of CEL) |
Processed data included within Sample table |
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