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| Status |
Public on Oct 30, 2018 |
| Title |
Coding and Non-coding gene expression signatures of granulosa cells from Polycystic Ovary Syndrome Patients |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Polycystic ovary syndrome (PCOS), one of the most common endocrinal diseases among reproductive-aged women,is characterized by hyperandrogenemia, chronic oligo/anovulation and polycystic ovarian morphology. In this research, we presented microarrays to identify the differential expressed protein-coding genes and lncRNAs expression profile in the luteinized granulosa cells obtained from PCOS and healthy control patients.
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| Overall design |
The human luteinized granulosa cells (hLGCs) were retrieved from the follicular fluid of normal and PCOS woman undergoing IVF or ICSI. RNA was extracted and hybridized to microarray screening of non-coding RNAs and mRNAs.
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| Contributor(s) |
Du YZ, Zhao J, Xu JY, Liu XJ, Geng XY |
| Citation(s) |
30293818 |
| Submission date |
May 14, 2018 |
| Last update date |
Oct 30, 2018 |
| Contact name |
Jun Zhao |
| E-mail(s) |
Jzhao_91@sjtu.edu.cn
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| Organization name |
Shanghai Jiao Tong university
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| Department |
Renji Hospital, School of medicine
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| Lab |
Center for Reproductive Medicine
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| Street address |
845 Lingshan Road
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| City |
Shanghai |
| ZIP/Postal code |
200135 |
| Country |
China |
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| Platforms (1) |
| GPL17586 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA471318 |
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