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Status |
Public on Jun 01, 2018 |
Title |
Overexpression of chicken IRF7 increased viral replication and programmed cell death to the avian influenza virus infection through TGF-beta/FoxO signaling axis in DF-1 |
Organism |
Gallus gallus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
To elucidate the functional role of chicken IRF7 against avian influenza virus (AIV) infection, we generated inducible IRF7 overexpression DF-1 cell lines that could fine control the IRF7 expression level and performed in vitro infection using low pathogenic AIVs (LPAIVs) followed by RNA-seq.
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Overall design |
Transcriptiome analysis of either low pathgenic influenza virus (H6N2) or mock infected chicken IRF7 overexpression DF-1 cell lines and respective control cell line
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Contributor(s) |
Kim T, Zhou H |
Citation(s) |
30356848 |
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Submission date |
May 30, 2018 |
Last update date |
Oct 29, 2018 |
Contact name |
Huaijun Zhou |
E-mail(s) |
hzhou@ucdavis.edu
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Organization name |
UC Davis
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Street address |
Meyer 3307, One shields Ave.
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City |
Davis |
State/province |
CA |
ZIP/Postal code |
95616 |
Country |
USA |
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Platforms (1) |
GPL23499 |
Illumina HiSeq 4000 (Gallus gallus) |
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Samples (8)
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Relations |
BioProject |
PRJNA473844 |
SRA |
SRP149379 |