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Status |
Public on Apr 10, 2020 |
Title |
Effects of hemocyte ablation on fat body gene expression |
Organism |
Anopheles gambiae |
Experiment type |
Expression profiling by high throughput sequencing
|
Summary |
To test the contributions of phagocytic immune cells to mosquito immunity, we depleted mosquito phagocytes using clodronate liposomes and then challenged mosquitoes with malaria parasites. Observing a large increase in infection intensity, the purpose of the RNA-seq experiment is to determine their effects of phagocyte depletion on mosquito immunity.
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Overall design |
Control and experimental samples were collected ~24hrs after infection with the rodent malaria parasite, P. berghei.
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Contributor(s) |
Smith RC |
Citation(s) |
31235594 |
Submission date |
Jun 22, 2018 |
Last update date |
Apr 10, 2020 |
Contact name |
Andrew J Severin |
E-mail(s) |
severin@iastate.edu
|
Phone |
5152941320
|
Organization name |
Iowa State University
|
Department |
Office of Biotechnology
|
Lab |
448 Bessey Hall (Genome Informatics Facility)
|
Street address |
2200 Osborn Drive
|
City |
Ames |
State/province |
IA |
ZIP/Postal code |
50014 |
Country |
USA |
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Platforms (1) |
GPL25232 |
Illumina HiSeq 3000 (Anopheles gambiae) |
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Samples (8)
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Relations |
BioProject |
PRJNA477466 |
SRA |
SRP151112 |