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| Status |
Public on Feb 13, 2020 |
| Title |
Dynamics of the transcriptional landscape during human gonad development during fetal life |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Fetal life is a crucial period for sexual reproduction when bipotential gonads differentiate into either a testis or an ovary. Gaining insights into the complex molecular events underlying this process is central to a better understanding of disorders of sexual development. The present work therefore intends to improve the knowledge on molecular pathways at play during gonad development in humans using RNA-Sequencing.
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| Overall design |
To define the transcriptional landscape of fetal human gonad in greater detail, we extracted and sequenced RNA (library Ribozero, 2x50 pb paired-end, strand specific, on Illumina HiSeq 2500) from testes and ovaries at 6, early 7, late 7, 9, 12, 13-14 and 17 weeks of gestation (n=4 or 2).
The 'Supplementary_table_for_GEO.xlsx' contains all of the information associated with the reconstructed transcripts.
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| Contributor(s) |
Lecluze E, Rolland AD, Chalmel F |
| Citation(s) |
32412604 |
| Submission date |
Jun 26, 2018 |
| Last update date |
Jun 10, 2020 |
| Contact name |
Frédéric Chalmel |
| E-mail(s) |
frederic.chalmel@inserm.fr
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| Organization name |
Inserm U1085-Irset
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| Department |
Physiology and physiopathology of the urogenital tract
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| Street address |
9 avenue du Pr. Léon Bernard
|
| City |
Rennes |
| State/province |
France |
| ZIP/Postal code |
35000 |
| Country |
France |
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| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
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| Samples (48)
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| Relations |
| BioProject |
PRJNA478051 |
| SRA |
SRP151462 |
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