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Series GSE117012 Query DataSets for GSE117012
Status Public on Jul 13, 2018
Title CD73 knockdown effect in pancreatic cancer cell lines
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Recent studies have shown that non-enzymatic function of CD73 play a key role in tumor progression, but this function of CD73 in pancreatic cancer cells has not been studied. In the present study, PANC-1 cell lines were transfected with CD73 siRNA, and proliferation ability and cell cycle was significantly inhibited. However, little is known about the mechanisms involved in CD73 regulation in tumors.
 
Overall design Six sampels including three CD73 knockdown cells by siRNA and three negative control cell lines were used.
 
Contributor(s) Zhou L, Jia S
Citation(s) 30927045
Submission date Jul 12, 2018
Last update date Jun 21, 2019
Contact name Liangjing Zhou
E-mail(s) 124929619@qq.com
Organization name Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China
Department Department of General Surgery
Street address no. 3,QingChun east road,Jianggan District, Hangzhou City, Zhejiang Province
City Hangzhou City, Zhejiang Province
ZIP/Postal code 310000
Country China
 
Platforms (1)
GPL20795 HiSeq X Ten (Homo sapiens)
Samples (6)
GSM3267325 PANC-1 CD73si1
GSM3267326 PANC-1 CD73si2
GSM3267327 PANC-1 CD73si3
Relations
BioProject PRJNA480855
SRA SRP153175

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE117012_RAW.tar 1.5 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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