|
| Status |
Public on Oct 01, 2018 |
| Title |
PPARg Deficiency Suppresses the Release of IL-1b and a in Macrophages via a Type 1 Interferon Dependent Mechanism |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
TG elicited Peritoneal macrophages from WT and PPARgamma KO mice were treated with control or lipid inflammatory stress in triplicate
|
| |
|
| Overall design |
LysM-Cre (cre) controls) or LysM-PPARg (ppar) were treated with vehicle (BSA-PBS; bp) or palmitate (250 uM) with LPS (100 ng/ml); pl for 8h and RNA was extracted
|
| |
|
| Contributor(s) |
Schilling J |
| Citation(s) |
30143592 |
| Submission date |
Jul 13, 2018 |
| Last update date |
Feb 11, 2019 |
| Contact name |
Joel D Schilling |
| E-mail(s) |
jschilli@dom.wustl.edu
|
| Phone |
314-747-8499
|
| Organization name |
Washington University School of Medicine
|
| Department |
Internal Medicine
|
| Lab |
Schilling lab
|
| Street address |
660 S. Euclid Ave
|
| City |
St. Louis |
| State/province |
MO |
| ZIP/Postal code |
63110 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL21493 |
Illumina HiSeq 3000 (Mus musculus) |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA481067 |
| SRA |
SRP153424 |
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