|
| Status |
Public on Oct 31, 2018 |
| Title |
Transcriptome Sequence of Antibiotic-Treated Pseudomonas aeruginosa |
| Organism |
Pseudomonas aeruginosa |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Pseudomonas aeruginosa is known to tolerate antibiotic therapy during infection. This prevents clearance of infection and negatively impacts patient outcomes. Here, we report the transcriptome sequence of antibiotic-treated and untreated P. aeruginosa cultures and the differential gene expression observed when treated cells are compared to untreated cells.
|
| |
|
| Overall design |
P. aeruginosa antibiotic tolerance, biofilm, planktonic, and stationary cultures
|
| |
|
| Contributor(s) |
Saika E, Tsute TC, Leung KP, Van Laar TA |
| Citation(s) |
30938705 |
| |
| Submission date |
Sep 28, 2018 |
| Last update date |
Apr 23, 2019 |
| Contact name |
Tsute Chen |
| E-mail(s) |
tchen@forsyth.org
|
| Phone |
617-892-8359
|
| Organization name |
The Forsyth Institute
|
| Department |
Microbiology
|
| Lab |
Chen
|
| Street address |
245 First Street
|
| City |
Cambridge |
| State/province |
MA |
| ZIP/Postal code |
02142 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL18644 |
Illumina HiSeq 2000 (Pseudomonas aeruginosa) |
|
| Samples (8)
|
| GSM3405609 |
Persister cells - cells treated with ciprofloxacin 1 |
| GSM3405610 |
Persister cells - cells treated with ciprofloxacin 2 |
| GSM3405611 |
Stationary cells - cells not treated with ciprofloxacin 1 |
| GSM3405612 |
Stationary cells - cells not treated with ciprofloxacin 2 |
| GSM3405613 |
Planktonic cells - cells grown in LB 1 |
| GSM3405614 |
Planktonic cells - cells grown in LB 2 |
| GSM3405615 |
Biofilms formed in LB on borosilicate glass discs 1 |
| GSM3405616 |
Biofilms formed in LB on borosilicate glass discs 2 |
|
| Relations |
| BioProject |
PRJNA493733 |
| SRA |
SRP162817 |
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