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| Status |
Public on Dec 31, 2018 |
| Title |
An atlas of genetic influences on osteoporosis in humans and mice |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
In our study, we leveraged RNA-seq data from four different human osteoblast cell lines and ATAC-seq data from one human osteoblast cell line to identify target genes for plausibly causal SNPs influencing bone density. We also re-called ENCODE generated osteoblast DNase hypersensitive sites, and have uploaded them here for sharing.
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| |
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| Overall design |
RNA-seq in four human osteoblast cell lines and ATAC-seq in one human osteoblast cell line. DHS re-called from ENCODE primary osteoblast data. Dnase-seq data obtained from ENCODE under accessions ENCLB776DWN and ENCLB906BCL
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| |
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| Contributor(s) |
Morris JA, Richards B |
| Citation(s) |
30598549 |
| |
| Submission date |
Oct 02, 2018 |
| Last update date |
Mar 21, 2019 |
| Contact name |
John A Morris |
| E-mail(s) |
jmorris@nygenome.org
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| Organization name |
New York Genome Center
|
| Street address |
101 Avenue of the Americas, 4th Floor
|
| City |
New York |
| State/province |
New York |
| ZIP/Postal code |
10013 |
| Country |
USA |
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| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
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| Samples (5)
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| Relations |
| BioProject |
PRJNA494401 |
| SRA |
SRP163143 |
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