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Status |
Public on Dec 31, 2018 |
Title |
An atlas of genetic influences on osteoporosis in humans and mice |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by high throughput sequencing Genome binding/occupancy profiling by high throughput sequencing
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Summary |
In our study, we leveraged RNA-seq data from four different human osteoblast cell lines and ATAC-seq data from one human osteoblast cell line to identify target genes for plausibly causal SNPs influencing bone density. We also re-called ENCODE generated osteoblast DNase hypersensitive sites, and have uploaded them here for sharing.
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Overall design |
RNA-seq in four human osteoblast cell lines and ATAC-seq in one human osteoblast cell line. DHS re-called from ENCODE primary osteoblast data. Dnase-seq data obtained from ENCODE under accessions ENCLB776DWN and ENCLB906BCL
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Contributor(s) |
Morris JA, Richards B |
Citation(s) |
30598549 |
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Submission date |
Oct 02, 2018 |
Last update date |
Mar 21, 2019 |
Contact name |
John A Morris |
E-mail(s) |
jmorris@nygenome.org
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Organization name |
New York Genome Center
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Street address |
101 Avenue of the Americas, 4th Floor
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City |
New York |
State/province |
New York |
ZIP/Postal code |
10013 |
Country |
USA |
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Platforms (1) |
GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
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Samples (5)
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Relations |
BioProject |
PRJNA494401 |
SRA |
SRP163143 |