|
| Status |
Public on Oct 12, 2018 |
| Title |
Effect of Influenza virus infection on lncRNA expression in A549 cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
Non-coding RNA profiling by high throughput sequencing
|
| Summary |
Long non-coding RNAs (lncRNAs) are a new arm of gene regulatory mechanism as discovered by sequencing techniques and follow-up functional studies. There are only few studies on lncRNAs as related to gene expression regulation and anti-viral activity during influenza virus infection. We sought to identify and characterize lncRNAs involved in influenza virus replication. In the current study, we identified dys-regulated lncRNAs in influenza virus-infected human lung epithelial A549 cells using RNA sequencing in A549 cells.
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| |
|
| Overall design |
RNA sequencing of A549 cells with Influenza virus and MOCK infection.
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| |
|
| Contributor(s) |
Huang C, Liu L, More S |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Oct 11, 2018 |
| Last update date |
Mar 26, 2019 |
| Contact name |
CHAOQUN HUANG |
| E-mail(s) |
chaoqh@okstate.edu
|
| Phone |
405-744-3410
|
| Organization name |
Oklahoma State University
|
| Department |
Physiological Sciences
|
| Lab |
Lundberg-Kienlen Lung Biology and Toxicology Laboratory
|
| Street address |
264 McElroy Hall
|
| City |
Stillwater |
| State/province |
OK |
| ZIP/Postal code |
74078 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
| Samples (6)
|
| GSM3427037 |
A549 cells treated with PBS replicate 1 |
| GSM3427038 |
A549 cells treated with PBS replicate 2 |
| GSM3427039 |
A549 cells treated with PBS replicate 3 |
| GSM3427040 |
A549 cells infected by Influenza virus PR8 replicate 1 |
| GSM3427041 |
A549 cells infected by Influenza virus PR8 replicate 2 |
| GSM3427042 |
A549 cells infected by Influenza virus PR8 replicate 3 |
|
| Relations |
| BioProject |
PRJNA495858 |
| SRA |
SRP165235 |
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