|
| Status |
Public on Oct 31, 2018 |
| Title |
Transciptome changes in relation to manic episode |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
The present study focused on manic episode in bipolar disorder (BD) patients, and to investigate state-specific transcriptome alterations between acute episode and remission, including mRNAs, long non-coding RNAs (lncRNAs), and miRNAs using Affymetrix Human Transcriptome Array 2.0.
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| |
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| Overall design |
Six BD patients were enrolled with clinical and biological samples collected at both acute and remission status following-up for at least two-months. We extracted RNA from two time points and used Affymetrix Human Transcriptome 2.0 array to capture transcriptome data underwent intra-individual comparison.
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| |
|
| Contributor(s) |
Lee Y, Chao Y, Chang C, Hsieh M, Liu K, Chen H, Lu M, Chen W, Chen C, Tsai M, Lu T, Huang M, Kuo P |
| Citation(s) |
31118907 |
| Submission date |
Oct 30, 2018 |
| Last update date |
May 26, 2019 |
| Contact name |
Ya-Chin Lee |
| E-mail(s) |
yachinglee1003@gmail.com
|
| Organization name |
National Taiwan University
|
| Department |
Institute of Epidemiology and Preventive Medicine
|
| Lab |
Human Genetics and Psychiatric Epidemiology
|
| Street address |
Rm 521, No.17, Xu-Zhou Rd.
|
| City |
Taipei |
| ZIP/Postal code |
10055 |
| Country |
Taiwan |
| |
|
| Platforms (1) |
| GPL17586 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
|
| Samples (12)
|
| GSM3450542 |
BD patient blood sample in manic episode [422220-1] |
| GSM3450543 |
BD patient blood sample in remission [422220-2] |
| GSM3450544 |
BD patient blood sample in manic episode [422520-1] |
| GSM3450545 |
BD patient blood sample in remission [422520-2] |
| GSM3450546 |
BD patient blood sample in manic episode [422720-1] |
| GSM3450547 |
BD patient blood sample in remission [422720-2] |
| GSM3450548 |
BD patient blood sample in manic episode [422820-1] |
| GSM3450549 |
BD patient blood sample in remission [422820-2] |
| GSM3450550 |
BD patient blood sample in manic episode [423120-1] |
| GSM3450551 |
BD patient blood sample in remission [423120-2] |
| GSM3450552 |
BD patient blood sample in manic episode [423820-1] |
| GSM3450553 |
BD patient blood sample in remission [423820-2] |
|
| Relations |
| BioProject |
PRJNA501805 |
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