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Status |
Public on Nov 02, 2018 |
Title |
Loss of the FAT1 tumor suppressor promotes resistance to CDK4/6 inhibitors via the Hippo pathway |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by high throughput sequencing
|
Summary |
Loss of FAT1 promotes resistance to CDK4/6 inhibitors. This study was to compare the differential mRNA expression of FAT1 crispr cells with parental cells, to identify the underlying mechanisms of resistance.
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Overall design |
Examnination of differential RNA expression in FAT1 loss cells compared to MCF-7 parental cells.
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Contributor(s) |
Chandarlapaty S, Li Q |
Citation(s) |
30537512, 32907621 |
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Submission date |
Nov 01, 2018 |
Last update date |
Sep 21, 2020 |
Contact name |
Sarat CHANDARLAPATY |
Organization name |
Memorial Sloan-Kettering Cancer Center
|
Department |
HOPP
|
Street address |
417 E 68th Street
|
City |
NEW YORK |
ZIP/Postal code |
10065 |
Country |
USA |
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Platforms (1) |
GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
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Samples (4)
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Relations |
BioProject |
PRJNA503479 |
SRA |
SRP167647 |