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Series GSE123106 Query DataSets for GSE123106
Status Public on Nov 30, 2018
Title Pseudomonas aeruginosa CLJ1 genome sequencing, transcriptomics, and proteomics [transcriptomics]
Organism Pseudomonas aeruginosa
Experiment type Expression profiling by high throughput sequencing
Summary Gene expression profiles of two Pseudomonas aeruginosa taxonomic outlier clinical isolates, CLJ1 and CLJ3 [CLJ1]

Pseudomonas aeruginosa taxonomic outliers emerged recently as infectious for humans, provoking hemorrhagic pneumonia. Those bacteria lack classical type III secretion system, and utilize the pore-forming toxin for infection. Two clones CLJ1 and CLJ3 belonging to these taxonomic outliers have been isolated from the same patient at two different times during hospitalization. P. aeruginosa CLJ3 displays antibiotic resistance phenotype, while CLJ1 is more cytotoxic on epithelial and endothelial cells.
 
Overall design Total RNA was isolated from CLJ1 and sequenced in duplicate using Illumina HiSeq to compare their genome-wide transcription levels and relate these to protein levels and genome sequence.
 
Contributor(s) Attrée I, Sentausa E
Citation(s) 30946644
BioProject PRJNA383797
Submission date Nov 29, 2018
Last update date Nov 16, 2020
Contact name Ina Attrée
E-mail(s) ina.attree-delic@cea.fr
Organization name Biosciences and Biotechnology Institute of Grenoble
Department Laboratory Biology of Cancer and Infection
Lab Bacterial Pathogenesis and Cellular Responses
Street address 17 avenue des Martyrs
City Grenoble
ZIP/Postal code 38054
Country France
 
Platforms (1)
GPL18644 Illumina HiSeq 2000 (Pseudomonas aeruginosa)
Samples (2)
GSM3495865 CLJ1-RNA1
GSM3495866 CLJ1-RNA2
Relations
SRA SRP170343

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE123106_RAW.tar 60.0 Kb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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