|
| Status |
Public on Jun 07, 2024 |
| Title |
Genome-wide chromatin localization profiling of transcription factor MML-1 |
| Organism |
Caenorhabditis elegans |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
MML-1 (Myc and Mondo-Like) encodes a Myc superfamily protein which, together with its partner MXL-2 (Max-like), regulates lifespan via distinct gene sets important for longevity. It is also required for normal migration of ray precursor cells in the male tail and for proper epidermal expression of extracellular matrix component genes. MML-1 binds to MXL-2, required for its protein stability. The MML-1/MXL-2 complex activate transcription mostly via E-box elements.
|
| |
|
| Overall design |
Profiling of MML-1 chromatin localization in wild-type third larval (L3) stage Caenorhabditis elegans
|
| |
|
| Contributor(s) |
Esse R, Grishok A |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Dec 06, 2018 |
| Last update date |
Jun 07, 2024 |
| Contact name |
Ruben Esse |
| E-mail(s) |
ruben.esse@kcl.ac.uk
|
| Organization name |
King’s College London
|
| Department |
Department of Medical and Molecular Genetics
|
| Street address |
Guy's Hospital, Great Maze Pond
|
| City |
London |
| ZIP/Postal code |
SE1 9RT |
| Country |
United Kingdom |
| |
|
| Platforms (1) |
| GPL19757 |
Illumina NextSeq 500 (Caenorhabditis elegans) |
|
| Samples (4)
|
|
| Relations |
| BioProject |
PRJNA508616 |
| SRA |
SRP172685 |
Less...
More...