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Status |
Public on Dec 13, 2018 |
Title |
The circadian clock components BMAL1 and REV-ERB? regulate flavivirus replication |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
We investigated the effect of the REV-ERB agonists on human hepatocytes. Since SR9009 showed the highest anti-viral activity and has been extensively studied in vivo we performed a whole genome microarray on SR9009 (20 µM) treated Huh-7 cells
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Overall design |
Two-condition experiment, Ctrl. vs. SR9009 treatment. Biological replicates: 3 control replicates, 3 treatment replicates.
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Contributor(s) |
Zhuang X, McKeating J |
Citation missing |
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Submission date |
Dec 12, 2018 |
Last update date |
Dec 14, 2018 |
Contact name |
Xiaodong Zhuang |
E-mail(s) |
xiaodong.zhuang@ndm.ox.ac.uk
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Organization name |
University of Oxford
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Street address |
Old Road Campus, Roosevelt Drive
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City |
Oxford |
State/province |
Oxfordshire |
ZIP/Postal code |
OX3 7FZ |
Country |
United Kingdom |
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Platforms (1) |
GPL20844 |
Agilent-072363 SurePrint G3 Human GE v3 8x60K Microarray 039494 [Feature Number Version] |
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Samples (6)
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Relations |
BioProject |
PRJNA509679 |