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| Status |
Public on Jan 11, 2019 |
| Title |
ERK2-dependent gene expression |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
ERK is a key coordinator of the epithelial to mesenchymal transition (EMT). However, the mechanisms by which ERK controls the EMT program are not well understood. We used microarray to determine global changes of gene expression mediated by ERK2.
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| Overall design |
Vector control, D319N ERK2, and Y261A ERK2 expression was induced by doxycycline in Tet-on MCF10A cell systems. Cells were grown for 7 days, and RNAs were purified from three individual replicates of each condition and microarray was performed.
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| Contributor(s) |
Shin S, Yoon S, Blenis J |
| Citation(s) |
30728292 |
| Submission date |
Jan 10, 2019 |
| Last update date |
Apr 12, 2019 |
| Contact name |
Sejeong Shin |
| E-mail(s) |
shin2016@uic.edu
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| Phone |
3096808600
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| Organization name |
University of Illinois at Chicago
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| Street address |
1 illini drive
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| City |
Peoria |
| State/province |
Illinois |
| ZIP/Postal code |
61656 |
| Country |
USA |
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| Platforms (1) |
| GPL17586 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
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| Samples (9)
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| Relations |
| BioProject |
PRJNA514405 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE124947_RAW.tar |
226.0 Mb |
(http)(custom) |
TAR (of CEL, CHP) |
| Processed data included within Sample table |
| Processed data provided as supplementary file |
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