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| Status |
Public on Jan 11, 2022 |
| Title |
Smilax glabra flavonoids treatment of 3T3-L1 adipocytes |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Smilax glabra Roxb, a traditional Chinese herb, has been widely used for folk medicine. Previous studies have found that it has various pharmacological activities, such as cytotoxic, anti-inflammation, anti-oxidant, hepatoprotective, and cardiovascular system protective activities. However, its roles in adipogenesis are poorly understood. We hypothesized that Smilax glabra Roxb and its main component may play important roles in regulating adipocyte diffrentiation and function. To test this hypothesis, we performed RNA-Seq on 3T3-L1 adipocytes treated with and without pure total flavonoids from Smilax glabra Roxb.
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| Overall design |
mRNA profiles of 3T3-L1 adipocytes (8 days after differentiation) treated with and without Smilax glabra flavonoids were generated by deep sequencing, in triplicate, using Illumina HiSeq.
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| Web link |
https://pubmed.ncbi.nlm.nih.gov/32106371/
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| |
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| Contributor(s) |
Cai Z |
| Citation(s) |
32106371 |
| |
| Submission date |
Jan 11, 2019 |
| Last update date |
Jan 11, 2022 |
| Contact name |
zhaowei cai |
| E-mail(s) |
zwc_zjtcm@hotmail.com
|
| Phone |
+86 571 86613662
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| Organization name |
zhejiang chinese medical university
|
| Department |
Laboratory Animal Research Center
|
| Street address |
Binwen road 548
|
| City |
Hangzhou |
| State/province |
Zhejiang |
| ZIP/Postal code |
310053 |
| Country |
China |
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| Platforms (1) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA514444 |
| SRA |
SRP178455 |
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