|
| Status |
Public on Sep 21, 2019 |
| Title |
Translational profiling of proximal tubule in fibrotic kidney |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Injury to the proximal tubule plays a central role in the initiation and progression of kidney fibrosis, and rates of chronic kidney disease progresses approximately 50% faster in males compared to females. We applied Translating Ribosome Affinity Purification (TRAP) followed by RNA-sequencing to characterize the cell-specific proximal tubule transcriptional landscape during fibrosis in male vs. female mice.
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| |
|
| Overall design |
Promixal tubule was profiled by Translating Ribosome Affinity Purification (TRAP)
|
| |
|
| Contributor(s) |
Humphreys BD |
| Citation(s) |
31537650 |
| |
| Submission date |
Jan 13, 2019 |
| Last update date |
Dec 21, 2019 |
| Contact name |
Haojia Wu |
| E-mail(s) |
haojiawu@wustl.edu
|
| Organization name |
Washington University in St. Louis
|
| Department |
Renal Division/Internal Medicine
|
| Lab |
Humphreys Lab
|
| Street address |
600 S Euclid Ave
|
| City |
St. Louis |
| State/province |
Missouri |
| ZIP/Postal code |
MO 63110 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL21493 |
Illumina HiSeq 3000 (Mus musculus) |
|
| Samples (42)
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|
| Relations |
| BioProject |
PRJNA514912 |
| SRA |
SRP178890 |
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