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Series GSE125515 Query DataSets for GSE125515
Status Public on Jan 14, 2022
Title Arabidopsis thaliana FIBRILLIN6 is involved in acclimation to moderate light stress and cadmium tolerance
Organism Arabidopsis thaliana
Experiment type Expression profiling by high throughput sequencing
Summary By mining public co-expression databases, we have identified FBN6 as a photosynthesis-associated gene. FBN6 is located in thylakoids and plastoglobules, and its knock-out results in stunted plants characterized by slightly reduced chlorophyll contents, shorter roots and late flowering under long-day conditions. The delayed growth phenotype of fbn6-1 cannot be attributed to altered basic photosynthesis parameters or a reduced CO2 assimilation rate. FBN6 is also co-expressed with redox/ROS-associated genes, and we show that under moderate light stress, the primary leaves of fbn6 plants begin to bleach and contain enlarged plastoglobules. Furthermore, anthocyanin accumulation is reduced in fbn6 mutants. RNA-Seq and metabolomics analyses point to an altered sulfate assimilation leading to accumulation of reduced glutathione which in turn confers cadmium tolerance of fbn6 seedlings.
 
Overall design Examination of differential gene expression in the Arabdidopsis thaliana fbn6-1 mutant compared to wild type in three replicates
 
Contributor(s) Kleine T
Citation(s) 31596965
Submission date Jan 23, 2019
Last update date May 11, 2022
Contact name Tatjana Kleine
E-mail(s) tatjana.kleine@lmu.de
Organization name Ludwig-Maximilians-Universität München
Department Biologie I, Botanik
Lab Dario Leister
Street address Großhaderner Straße 2
City Planegg
ZIP/Postal code 82152
Country Germany
 
Platforms (1)
GPL17639 Illumina HiSeq 2500 (Arabidopsis thaliana)
Samples (6)
GSM3576285 Col_2-RNAseq
GSM3576286 Col_3-RNAseq
GSM3576287 Col_4-RNAseq
Relations
BioProject PRJNA516656
SRA SRP181647

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE125515_RAW.tar 780.0 Kb (http)(custom) TAR (of TAB)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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