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Series GSE126462 Query DataSets for GSE126462
Status Public on Feb 13, 2019
Title Chaetocin Mediated Changes in Gene Expression Profile of GBM Cells
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Chaetocin treatment significantly modulated expression profile of GBM cells such that 373 genes were up and 478 genes were down regulated significantly (FDR<0.05). Genes involved in DNA damage response, reactive oxygen species pathway and cell cycle regulation as well as epithelial to mesenchymal transition are significantly modified by Chaetocin, which render GBM cells much more prone to apoptosis.
Overall design Examination of Chaetocin's effect on gene expression profile of U87MG cells. 2 sets of samples were prepared for Chaetocin treated (50 nM, 24h) and untreated (control) conditions.
Contributor(s) Bagci-Onder T, Özyerli-Göknar E, Uyulur F
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Submission date Feb 12, 2019
Last update date Mar 21, 2019
Contact name Tugba Bagci-Onder
Phone +90 212 338 1077
Organization name Koc University
Department School of Medicine
Lab Brain Cancer Research and Therapy Lab
Street address Koc University School of Medicine
City Istanbul
State/province Sariyer
ZIP/Postal code 34450
Country Turkey
Platforms (1)
GPL20301 Illumina HiSeq 4000 (Homo sapiens)
Samples (4)
GSM3602128 Control rep1
GSM3602129 Control rep2
GSM3602130 Chae rep1
BioProject PRJNA521979
SRA SRP185721

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE126462_RAW.tar 980.0 Kb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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