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Series GSE126601 Query DataSets for GSE126601
Status Public on Feb 16, 2019
Title Genome-wide map of viral transcription factor ORF34 binding in Kaposi's Sarcoma Herpesvirus (KSHV)
Organisms Homo sapiens; Human gammaherpesvirus 8
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary We report the mapping of the genome-wide binding sites of a central component of a viral transcription complex from KSHV. We find that ORF34 binds at several locations on the viral genome but observed no detectable binding to the host genome. A majority of binding sites on the viral genome were upstream of known transcription start sites of mapped genes.
Overall design Chromatin for immuno-precipitation was prepared from iSLK cells latently infected with HA-ORF34 KSHV and reactivated with doxycycline and sodium butyrate for 48 h.
Contributor(s) Nandakumar D, Glaunsinger B
Citation(s) 31095645
Submission date Feb 14, 2019
Last update date May 20, 2019
Contact name Britt Glaunsinger
Organization name UC Berkeley
Street address 565 Li Ka Shing Center
City Berkeley
State/province CA
ZIP/Postal code 94720
Country USA
Platforms (1)
GPL25719 Illumina HiSeq 4000 (Homo sapiens; Human gammaherpesvirus 8)
Samples (8)
GSM3609577 WT-ChIP-Rep1
GSM3609578 HA-ChIP-Rep1
GSM3609579 WT-Input-Rep1
This SubSeries is part of SuperSeries:
GSE126603 An integrative approach identifies direct targets of the late viral transcription complex and an expanded promoter recognition motif in Kaposi’s sarcoma-associated herpesvirus
BioProject PRJNA522742
SRA SRP185998

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE126601_RAW.tar 2.7 Gb (http)(custom) TAR (of TDF)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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