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| Status |
Public on Feb 19, 2009 |
| Title |
Detection of chromosomal aberrations in renal tumors by virtual karyotyping with SNP microarrays |
| Organism |
Homo sapiens |
| Experiment type |
Genome variation profiling by SNP array
SNP genotyping by SNP array
|
| Summary |
Renal epithelial neoplasms have characteristic chromosomal imbalances that can be used for classification. We have previously shown that virtual karyotypes (v-karyotype) derived from SNP microarrays can be performed on formalin-fixed paraffin embedded (FFPE) tissue samples but a direct comparison with karyotypes obtained by conventional cytogenetics has not been done. 20 archival FFPE tumor samples were analyzed with Affymetrix 10K 2.0 or 250K Nsp SNP microarrays.
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| |
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| Overall design |
19 archival FFPE tumor samples were analyzed with Affymetrix 10K 2.0 or 250K Nsp SNP microarrays and virtual-karyotype results compared to those obtained by Cytogenetics.
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| Contributor(s) |
Monzon FA, Alvarez K, Bridge JA, Nelson M, Gatalica Z, Hagenkord J |
| Citation(s) |
19961245 |
| |
| Submission date |
Sep 16, 2008 |
| Last update date |
Oct 03, 2018 |
| Contact name |
Federico A Monzon |
| E-mail(s) |
famonzon@tmhs.org
|
| Organization name |
The Methodist Hospital Research Institute
|
| Department |
Pathology
|
| Street address |
6565 Fannin St., MS205
|
| City |
Houston |
| State/province |
TX |
| ZIP/Postal code |
77030 |
| Country |
USA |
| |
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| Platforms (2) |
| GPL2641 |
[Mapping10K_Xba142] Affymetrix Human Mapping 10K 2.0 Array |
| GPL3718 |
[Mapping250K_Nsp] Affymetrix Mapping 250K Nsp SNP Array |
|
| Samples (19)
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|
| Relations |
| BioProject |
PRJNA111115 |
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