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Status |
Public on Oct 27, 2008 |
Title |
Oncogenesis of T-ALL and non-malignant consequences of overexpressing NOTCH1 |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
|
Summary |
We have determined the consequences of ICN1 overexpression from retroviral vectors introduced into bone marrow cells. Even though the tumors consist of phenotypically heterogeneous cells, no evidence for tumor stem cells was found.
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Overall design |
Expression analysis, array-based comparative genomic hybridization and spectral karyotyping.
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Contributor(s) |
Li X, Gounari F, Protopopov A, Khazaie K, von Boehmer H |
Citation(s) |
18981238, 20007543 |
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Submission date |
Sep 26, 2008 |
Last update date |
Feb 11, 2019 |
Contact name |
Alexei Protopopov |
Organization name |
UT MD Anderson Cancer Center
|
Department |
IACS
|
Street address |
1901 East Rd
|
City |
Houston |
State/province |
TX |
ZIP/Postal code |
77054 |
Country |
USA |
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Platforms (1) |
GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
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Samples (9)
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Relations |
BioProject |
PRJNA110977 |