|
Status |
Public on Jun 11, 2019 |
Title |
Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes |
Organism |
Homo sapiens |
Experiment type |
Methylation profiling by genome tiling array
|
Summary |
We undertook a meta-analysis based on DNA methylation patterns of Group3/4 subgroup medulloblastoma from three published studies, alongside additional unpublished tumours (total n=1501).
|
|
|
Overall design |
We used 267 samples from GSE93646, 356 samples from GSE85212, 725 samples from Northcott et al., 2017 (PMID: 28726821) and 153 previously unpublished samples from the St. Jude collection. Bisulfite-converted DNA from medulloblastoma samples were hybridised to the Illumina Infinium 450k and Infinium MethylationEPIC BeadChips.
|
|
|
Contributor(s) |
Schwalbe EC, Sharma T |
Citation(s) |
31076851 |
|
Submission date |
Apr 18, 2019 |
Last update date |
Jun 20, 2019 |
Contact name |
Ed Schwalbe |
E-mail(s) |
ed.schwalbe@northumbria.ac.uk
|
Organization name |
Northumbria University
|
Department |
Applied Sciences
|
Street address |
Ellison Place
|
City |
Newcastle upon Tyne |
ZIP/Postal code |
NE1 8ST |
Country |
United Kingdom |
|
|
Platforms (2) |
GPL13534 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482) |
GPL21145 |
Infinium MethylationEPIC |
|
Samples (1501)
|
|
Relations |
BioProject |
PRJNA548386 |