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| Status |
Public on Jun 11, 2019 |
| Title |
Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by genome tiling array
|
| Summary |
We undertook a meta-analysis based on DNA methylation patterns of Group3/4 subgroup medulloblastoma from three published studies, alongside additional unpublished tumours (total n=1501).
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| |
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| Overall design |
We used 267 samples from GSE93646, 356 samples from GSE85212, 725 samples from Northcott et al., 2017 (PMID: 28726821) and 153 previously unpublished samples from the St. Jude collection. Bisulfite-converted DNA from medulloblastoma samples were hybridised to the Illumina Infinium 450k and Infinium MethylationEPIC BeadChips.
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| |
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| Contributor(s) |
Schwalbe EC, Sharma T |
| Citation(s) |
31076851 |
| |
| Submission date |
Apr 18, 2019 |
| Last update date |
Jun 20, 2019 |
| Contact name |
Ed Schwalbe |
| E-mail(s) |
ed.schwalbe@northumbria.ac.uk
|
| Organization name |
Northumbria University
|
| Department |
Applied Sciences
|
| Street address |
Ellison Place
|
| City |
Newcastle upon Tyne |
| ZIP/Postal code |
NE1 8ST |
| Country |
United Kingdom |
| |
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| Platforms (2) |
| GPL13534 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482) |
| GPL21145 |
Infinium MethylationEPIC |
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| Samples (1501)
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| Relations |
| BioProject |
PRJNA548386 |
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