|
| Status |
Public on May 29, 2019 |
| Title |
Chromatin accessiblity in mouse thymic epithelial cells to determine active regulatory elements. |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
The thymus is the site of T cell development. Although much is known about the development and differentiation of the T lymphocyte compartment, less is known about the thymic epithelial cell (TEC). Foxn1 is critical for the development and function of the thymus. Here, we used ATAC-Seq to identify regions of accessible chromatin in TEC and keratinocytes of the skin to identify candidate active regulatory elements critical for tissue specific expression of Foxn1.
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| |
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| Overall design |
ATAC-Seq was performed on sorted thymic epithelial cells and sorted keratinocytes of the skin
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| |
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| Contributor(s) |
Larsen B, Zhao Y, Voisin B, Nagao K, Bhandoola A |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
May 21, 2019 |
| Last update date |
May 31, 2019 |
| Contact name |
Yongge Zhao |
| E-mail(s) |
yongge.zhao@nih.gov
|
| Phone |
2407607622
|
| Organization name |
NCI
|
| Lab |
LGI
|
| Street address |
9000 Rockville Pike
|
| City |
Bethesda |
| State/province |
MD |
| ZIP/Postal code |
20892 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (10)
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|
| Relations |
| BioProject |
PRJNA544109 |
| SRA |
SRP199125 |
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