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Status |
Public on Jan 01, 2020 |
Title |
Divergences of sperm DNA methylomes between monozygotic twin seed bulls reveal fertility-related genes (RNA-Seq) |
Organism |
Bos taurus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
Semen quality is extremely important for fertility, and it is easily influenced by environmental factors and can induce subfertility of the next generations. The sperm DNA methylomes of the MZ twin bulls were investigated by WGBS at single-base resolution. We detected DMRs between the twin bulls with divergent sperm qualities. We also conducted transcriptome sequencing for the MZ twin bulls in three replicates. We investigated the relationship between methylation and gene expression.
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Overall design |
Comparison of sperm transcriptome profiles between monozygous twin bulls with divergent male fertility.
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Contributor(s) |
Liu S, Zhang S, Yu Y |
Citation(s) |
34968253, 37366074 |
Submission date |
May 28, 2019 |
Last update date |
Sep 12, 2023 |
Contact name |
Shengli Zhang |
E-mail(s) |
zhangslcau@cau.edu.cn
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Organization name |
China Agricultural University
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Department |
Colledge of Animal Science and Techonology
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Street address |
2rd, Yuanmingyuan West Road
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City |
Beijing |
ZIP/Postal code |
100193 |
Country |
China |
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Platforms (1) |
GPL23295 |
Illumina HiSeq 4000 (Bos taurus) |
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Samples (6)
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This SubSeries is part of SuperSeries: |
GSE131851 |
Divergences of sperm DNA methylomes between monozygotic twin seed bulls reveal fertility-related genes |
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Relations |
BioProject |
PRJNA545120 |
SRA |
SRP199654 |