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GEO accession:
Series GSE133203
Query DataSets for GSE133203
Status
Public on Jun 25, 2019
Title
Polymorphisms in RocA contribute to the molecular pathogenesis of serotype M28 group A streptococcus
Organism
Streptococcus pyogenes
Experiment type
Expression profiling by high throughput sequencing
Summary
RNA-seq experiments of serotype M28 group A streptococcus strains with mutations in rocA at two time points
Overall design
RNA-seq data 53 strains at 2 time points in duplicate (clinical isolates) and 7 strains at 2 time points in triplicate (isogenics)
Contributor(s)
Bernard PE
,
Olsen RJ
Citation(s)
31369755
BioProject
PRJNA540250
Submission date
Jun 24, 2019
Last update date
Sep 24, 2019
Contact name
Paul Bernard
E-mail(s)
pbernard@medicine.tamhsc.edu
Organization name
Houston Methodist Research Institute
Street address
6670 Bertner Ave
City
Houston
State/province
TX
ZIP/Postal code
77030
Country
USA
Platforms (1)
GPL24880
Illumina NextSeq 500 (Streptococcus pyogenes)
Samples (257)
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More...
GSM3902054
MGAS12241_ME_1 (Sample 1)
GSM3902055
MGAS12241_ME_2 (Sample 2)
GSM3902056
MGAS28166_ME_1 (Sample 3)
GSM3902057
MGAS28166_ME_2 (Sample 4)
GSM3902058
MGAS28204_ME_1 (Sample 5)
GSM3902059
MGAS28204_ME_2 (Sample 6)
GSM3902060
MGAS28245_ME_1 (Sample 7)
GSM3902061
MGAS28245_ME_2 (Sample 8)
GSM3902062
MGAS28253_ME_1 (Sample 9)
GSM3902063
MGAS28253_ME_2 (Sample 10)
GSM3902064
MGAS28299_ME_1 (Sample 11)
GSM3902065
MGAS28299_ME_2 (Sample 12)
GSM3902066
MGAS28411_ME_1 (Sample 13)
GSM3902067
MGAS28411_ME_2 (Sample 14)
GSM3902068
MGAS28553_ME_1 (Sample 15)
GSM3902069
MGAS28553_ME_2 (Sample 16)
GSM3902070
MGAS28632_ME_1 (Sample 17)
GSM3902071
MGAS28632_ME_2 (Sample 18)
GSM3902072
MGAS28677_ME_1 (Sample 19)
GSM3902073
MGAS28677_ME_2 (Sample 20)
GSM3902074
MGAS29160_ME_1 (Sample 21)
GSM3902075
MGAS29160_ME_2 (Sample 22)
GSM3902076
MGAS29250_ME_1 (Sample 23)
GSM3902077
MGAS29250_ME_2 (Sample 24)
GSM3902078
MGAS29251_ME_1 (Sample 25)
GSM3902079
MGAS29251_ME_2 (Sample 26)
GSM3902080
MGAS29298_ME_1 (Sample 27)
GSM3902081
MGAS29298_ME_2 (Sample 28)
GSM3902082
MGAS29336_ME_1 (Sample 29)
GSM3902083
MGAS29336_ME_2 (Sample 30)
GSM3902084
MGAS29395_ME_1 (Sample 31)
GSM3902085
MGAS29395_ME_2 (Sample 32)
GSM3902086
MGAS29454_ME_1 (Sample 33)
GSM3902087
MGAS29460_ME_1 (Sample 34)
GSM3902088
MGAS29460_ME_2 (Sample 35)
GSM3902089
MGAS29555_ME_1 (Sample 36)
GSM3902090
MGAS29555_ME_2 (Sample 37)
GSM3902091
MGAS29596_ME_1 (Sample 38)
GSM3902092
MGAS29596_ME_2 (Sample 39)
GSM3902093
MGAS10816_ME_1 (Sample 40)
GSM3902094
MGAS10816_ME_2 (Sample 41)
GSM3902095
MGAS11107_ME_1 (Sample 42)
GSM3902096
MGAS11107_ME_2 (Sample 43)
GSM3902097
MGAS12250_ME_1 (Sample 44)
GSM3902098
MGAS12250_ME_2 (Sample 45)
GSM3902099
MGAS27961_ME_1 (Sample 46)
GSM3902100
MGAS27961_ME_2 (Sample 47)
GSM3902101
MGAS28101_ME_1 (Sample 48)
GSM3902102
MGAS28101_ME_2 (Sample 49)
GSM3902103
MGAS28330_ME_1 (Sample 50)
GSM3902104
MGAS28330_ME_2 (Sample 51)
GSM3902105
MGAS28426_ME_1 (Sample 52)
GSM3902106
MGAS28426_ME_2 (Sample 53)
GSM3902107
MGAS28652_ME_1 (Sample 54)
GSM3902108
MGAS28652_ME_2 (Sample 55)
GSM3902109
MGAS28706_ME_1 (Sample 56)
GSM3902110
MGAS28706_ME_2 (Sample 57)
GSM3902111
MGAS28742_ME_1 (Sample 58)
GSM3902112
MGAS28742_ME_2 (Sample 59)
GSM3902113
MGAS28912_ME_1 (Sample 60)
GSM3902114
MGAS28912_ME_2 (Sample 61)
GSM3902115
MGAS28941_ME_1 (Sample 62)
GSM3902116
MGAS28941_ME_2 (Sample 63)
GSM3902117
MGAS29146_ME_1 (Sample 64)
GSM3902118
MGAS29146_ME_2 (Sample 65)
GSM3902119
MGAS29475_ME_1 (Sample 66)
GSM3902120
MGAS29475_ME_2 (Sample 67)
GSM3902121
MGAS31960_ME_1 (Sample 68)
GSM3902122
MGAS31960_ME_2 (Sample 69)
GSM3902123
MGAS31968_ME_1 (Sample 70)
GSM3902124
MGAS31968_ME_2 (Sample 71)
GSM3902125
MGAS31971_ME_1 (Sample 72)
GSM3902126
MGAS31971_ME_2 (Sample 73)
GSM3902127
MGAS31997_ME_1 (Sample 74)
GSM3902128
MGAS31997_ME_2 (Sample 75)
GSM3902129
MGAS32013_ME_1 (Sample 76)
GSM3902130
MGAS32013_ME_2 (Sample 77)
GSM3902131
MGAS32031_ME_1 (Sample 78)
GSM3902132
MGAS32031_ME_2 (Sample 79)
GSM3902133
MGAS7893_ME_1 (Sample 80)
GSM3902134
MGAS7893_ME_2 (Sample 81)
GSM3902135
MGAS7895_ME_1 (Sample 82)
GSM3902136
MGAS7895_ME_2 (Sample 83)
GSM3902137
MGAS7904_ME_1 (Sample 84)
GSM3902138
MGAS7904_ME_2 (Sample 85)
GSM3902139
MGAS7909_ME_1 (Sample 86)
GSM3902140
MGAS7909_ME_2 (Sample 87)
GSM3902141
MGAS7966_ME_1 (Sample 88)
GSM3902142
MGAS7966_ME_2 (Sample 89)
GSM3902143
MGAS7995_ME_1 (Sample 90)
GSM3902144
MGAS7995_ME_2 (Sample 91)
GSM3902145
MGAS8020_ME_1 (Sample 92)
GSM3902146
MGAS8020_ME_2 (Sample 93)
GSM3902147
MGAS28050_ME_1 (Sample 94)
GSM3902148
MGAS28050_ME_2 (Sample 95)
GSM3902149
MGAS28689_ME_1 (Sample 96)
GSM3902150
MGAS28689_ME_2 (Sample 97)
GSM3902151
MGAS29454_ME_3 (Sample 98)
GSM3902152
MGAS29454_ME_4 (Sample 99)
GSM3902153
MGAS29562_ME_1 (Sample 100)
GSM3902154
MGAS29562_ME_2 (Sample 101)
GSM3902155
MGAS32014_ME_1 (Sample 102)
GSM3902156
MGAS32014_ME_2 (Sample 103)
GSM3902157
MGAS7967_ME_1 (Sample 104)
GSM3902158
MGAS7967_ME_2 (Sample 105)
GSM3902159
delta_rocA_ME_1 (Sample 106)
GSM3902160
delta_rocA_ME_2 (Sample 107)
GSM3902161
MGAS12241_ES_1 (Sample 108)
GSM3902162
MGAS12241_ES_2 (Sample 109)
GSM3902163
MGAS28166_ES_1 (Sample 110)
GSM3902164
MGAS28166_ES_2 (Sample 111)
GSM3902165
MGAS28204_ES_1 (Sample 112)
GSM3902166
MGAS28204_ES_2 (Sample 113)
GSM3902167
MGAS28245_ES_1 (Sample 114)
GSM3902168
MGAS28245_ES_2 (Sample 115)
GSM3902169
MGAS28253_ES_1 (Sample 116)
GSM3902170
MGAS28253_ES_2 (Sample 117)
GSM3902171
MGAS28299_ES_1 (Sample 118)
GSM3902172
MGAS28299_ES_2 (Sample 119)
GSM3902173
MGAS28411_ES_1 (Sample 120)
GSM3902174
MGAS28411_ES_2 (Sample 121)
GSM3902175
MGAS28553_ES_1 (Sample 122)
GSM3902176
MGAS28553_ES_2 (Sample 123)
GSM3902177
MGAS28632_ES_1 (Sample 124)
GSM3902178
MGAS28632_ES_2 (Sample 125)
GSM3902179
MGAS28677_ES_1 (Sample 126)
GSM3902180
MGAS28677_ES_2 (Sample 127)
GSM3902181
MGAS29160_ES_1 (Sample 128)
GSM3902182
MGAS29160_ES_2 (Sample 129)
GSM3902183
MGAS29250_ES_1 (Sample 130)
GSM3902184
MGAS29250_ES_2 (Sample 131)
GSM3902185
MGAS29251_ES_1 (Sample 132)
GSM3902186
MGAS29251_ES_2 (Sample 133)
GSM3902187
MGAS29298_ES_1 (Sample 134)
GSM3902188
MGAS29298_ES_2 (Sample 135)
GSM3902189
MGAS29336_ES_1 (Sample 136)
GSM3902190
MGAS29336_ES_2 (Sample 137)
GSM3902191
MGAS29395_ES_1 (Sample 138)
GSM3902192
MGAS29395_ES_2 (Sample 139)
GSM3902193
MGAS29454_ES_1 (Sample 140)
GSM3902194
MGAS29454_ES_2 (Sample 141)
GSM3902195
MGAS29460_ES_1 (Sample 142)
GSM3902196
MGAS29460_ES_2 (Sample 143)
GSM3902197
MGAS29555_ES_1 (Sample 144)
GSM3902198
MGAS29555_ES_2 (Sample 145)
GSM3902199
MGAS29596_ES_1 (Sample 146)
GSM3902200
MGAS29596_ES_2 (Sample 147)
GSM3902201
MGAS10816_ES_1 (Sample 148)
GSM3902202
MGAS10816_ES_2 (Sample 149)
GSM3902203
MGAS11107_ES_1 (Sample 150)
GSM3902204
MGAS11107_ES_2 (Sample 151)
GSM3902205
MGAS12250_ES_1 (Sample 152)
GSM3902206
MGAS12250_ES_2 (Sample 153)
GSM3902207
MGAS27961_ES_1 (Sample 154)
GSM3902208
MGAS27961_ES_2 (Sample 155)
GSM3902209
MGAS28101_ES_1 (Sample 156)
GSM3902210
MGAS28101_ES_2 (Sample 157)
GSM3902211
MGAS28330_ES_1 (Sample 158)
GSM3902212
MGAS28330_ES_2 (Sample 159)
GSM3902213
MGAS28426_ES_1 (Sample 160)
GSM3902214
MGAS28426_ES_2 (Sample 161)
GSM3902215
MGAS28652_ES_1 (Sample 162)
GSM3902216
MGAS28652_ES_2 (Sample 163)
GSM3902217
MGAS28706_ES_1 (Sample 164)
GSM3902218
MGAS28706_ES_2 (Sample 165)
GSM3902219
MGAS28742_ES_1 (Sample 166)
GSM3902220
MGAS28742_ES_2 (Sample 167)
GSM3902221
MGAS28912_ES_1 (Sample 168)
GSM3902222
MGAS28912_ES_2 (Sample 169)
GSM3902223
MGAS28941_ES_1 (Sample 170)
GSM3902224
MGAS28941_ES_2 (Sample 171)
GSM3902225
MGAS29146_ES_1 (Sample 172)
GSM3902226
MGAS29146_ES_2 (Sample 173)
GSM3902227
MGAS29475_ES_1 (Sample 174)
GSM3902228
MGAS29475_ES_2 (Sample 175)
GSM3902229
MGAS31960_ES_1 (Sample 176)
GSM3902230
MGAS31960_ES_2 (Sample 177)
GSM3902231
MGAS31968_ES_1 (Sample 178)
GSM3902232
MGAS31968_ES_2 (Sample 179)
GSM3902233
MGAS31971_ES_1 (Sample 180)
GSM3902234
MGAS31971_ES_2 (Sample 181)
GSM3902235
MGAS31997_ES_1 (Sample 182)
GSM3902236
MGAS31997_ES_2 (Sample 183)
GSM3902237
MGAS32013_ES_1 (Sample 184)
GSM3902238
MGAS32013_ES_2 (Sample 185)
GSM3902239
MGAS32031_ES_1 (Sample 186)
GSM3902240
MGAS32031_ES_2 (Sample 187)
GSM3902241
MGAS7893_ES_1 (Sample 188)
GSM3902242
MGAS7893_ES_2 (Sample 189)
GSM3902243
MGAS7895_ES_1 (Sample 190)
GSM3902244
MGAS7895_ES_2 (Sample 191)
GSM3902245
MGAS7904_ES_1 (Sample 192)
GSM3902246
MGAS7904_ES_2 (Sample 193)
GSM3902247
MGAS7909_ES_1 (Sample 194)
GSM3902248
MGAS7909_ES_2 (Sample 195)
GSM3902249
MGAS7966_ES_1 (Sample 196)
GSM3902250
MGAS7966_ES_2 (Sample 197)
GSM3902251
MGAS7995_ES_1 (Sample 198)
GSM3902252
MGAS7995_ES_2 (Sample 199)
GSM3902253
MGAS8020_ES_1 (Sample 200)
GSM3902254
MGAS8020_ES_2 (Sample 201)
GSM3902255
MGAS28050_ES_1 (Sample 202)
GSM3902256
MGAS28050_ES_2 (Sample 203)
GSM3902257
MGAS28689_ES_1 (Sample 204)
GSM3902258
MGAS28689_ES_2 (Sample 205)
GSM3902259
MGAS29454_ES_3 (Sample 206)
GSM3902260
MGAS29454_ES_4 (Sample 207)
GSM3902261
MGAS29562_ES_1 (Sample 208)
GSM3902262
MGAS29562_ES_2 (Sample 209)
GSM3902263
MGAS32014_ES_1 (Sample 210)
GSM3902264
MGAS32014_ES_2 (Sample 211)
GSM3902265
MGAS7967_ES_1 (Sample 212)
GSM3902266
MGAS7967_ES_2 (Sample 213)
GSM3902267
delta_rocA_ES_1 (Sample 214)
GSM3902268
delta_rocA_ES_2 (Sample 215)
GSM3902269
delta_rocA_ES_1 (Sample 216)
GSM3902270
delta_rocA_ES_2 (Sample 217)
GSM3902271
delta_rocA_ES_3 (Sample 218)
GSM3902272
G184W_ES_1 (Sample 219)
GSM3902273
G184W_ES_2 (Sample 220)
GSM3902274
G184W_ES_3 (Sample 221)
GSM3902275
P97L_ES_1 (Sample 222)
GSM3902276
P97L_ES_2 (Sample 223)
GSM3902277
P97L_ES_3 (Sample 224)
GSM3902278
R258K_ES_1 (Sample 225)
GSM3902279
R258K_ES_2 (Sample 226)
GSM3902280
R258K_ES_3 (Sample 227)
GSM3902281
T442P_ES_1 (Sample 228)
GSM3902282
T442P_ES_2 (Sample 229)
GSM3902283
T442P_ES_3 (Sample 230)
GSM3902284
VNTR_H60Y_ES_1 (Sample 231)
GSM3902285
VNTR_H60Y_ES_2 (Sample 232)
GSM3902286
VNTR_H60Y_ES_3 (Sample 233)
GSM3902287
WT_ES_1 (Sample 234)
GSM3902288
WT_ES_2 (Sample 235)
GSM3902289
WT_ES_3 (Sample 236)
GSM3902290
delta_rocA_ME_1 (Sample 237)
GSM3902291
delta_rocA_ME_2 (Sample 238)
GSM3902292
delta_rocA_ME_3 (Sample 239)
GSM3902293
G184W_ME_1 (Sample 240)
GSM3902294
G184W_ME_2 (Sample 241)
GSM3902295
G184W_ME_3 (Sample 242)
GSM3902296
P97L_ME_1 (Sample 243)
GSM3902297
P97L_ME_2 (Sample 244)
GSM3902298
P97L_ME_3 (Sample 245)
GSM3902299
R258K_ME_1 (Sample 246)
GSM3902300
R258K_ME_2 (Sample 247)
GSM3902301
R258K_ME_3 (Sample 248)
GSM3902302
T442P_ME_1 (Sample 249)
GSM3902303
T442P_ME_2 (Sample 250)
GSM3902304
T442P_ME_3 (Sample 251)
GSM3902305
VNTR_H60Y_ME_1 (Sample 252)
GSM3902306
VNTR_H60Y_ME_2 (Sample 253)
GSM3902307
VNTR_H60Y_ME_3 (Sample 254)
GSM3902308
WT_ME_1 (Sample 255)
GSM3902309
WT_ME_2 (Sample 256)
GSM3902310
WT_ME_3 (Sample 257)
Download family
Format
SOFT formatted family file(s)
SOFT
MINiML formatted family file(s)
MINiML
Series Matrix File(s)
TXT
Supplementary file
Size
Download
File type/resource
GSE133203_Clinical_isolates_ES_v2.xlsx
1.3 Mb
(ftp)
(http)
XLSX
GSE133203_Clinical_isolates_ME_v2.xlsx
1.3 Mb
(ftp)
(http)
XLSX
GSE133203_Isogenics.xlsx
552.0 Kb
(ftp)
(http)
XLSX
SRA Run Selector
Raw data are available in SRA
Processed data are available on Series record
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