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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Oct 01, 2019 |
| Title |
Transcriptome profiles of antibody-producing CHO cells across different amplification strategies |
| Organism |
Cricetulus griseus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
The mechanism of action behind the increased secretion capacity of the amplified progeny of CHO cells is investigated in this study through comparative transcriptomic analysis
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| Overall design |
The amplified DG-44 CHO cells, taken at both exponential and stationary growth phase were compared to non-amplified CHO DG-44 cells. Non-producing CHO-S samples were used as negative controls.
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| Web link |
https://doi.org/10.1016/j.crbiot.2019.09.001
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| Contributor(s) |
Lewis NE |
| Citation(s) |
32577618 |
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| Submission date |
Jun 28, 2019 |
| Last update date |
Jun 29, 2020 |
| Contact name |
Nathan E Lewis |
| Organization name |
UCSD
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| Street address |
9500 Gilman Dr
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| City |
La Jolla |
| State/province |
CA |
| ZIP/Postal code |
92122 |
| Country |
USA |
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| Platforms (1) |
| GPL21152 |
Illumina MiSeq (Cricetulus griseus) |
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| Samples (24)
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| GSM3910581 |
CHO cells, A02_EXP_RLT |
| GSM3910582 |
CHO cells, A03_EXP_Duplicate |
| GSM3910583 |
CHO cells, A03_EXP |
| GSM3910584 |
CHO cells, A04_EXP_Duplicate |
| GSM3910585 |
CHO cells, A04_EXP |
| GSM3910586 |
CHO cells, A01_STA |
| GSM3910587 |
CHO cells, A02_STA |
| GSM3910588 |
CHO cells, A03_STA |
| GSM3910589 |
CHO cells, A04_STA |
| GSM3910590 |
CHO cells, A1-1_EXP |
| GSM3910591 |
CHO cells, A1-2_EXP |
| GSM3910592 |
CHO cells, A1-3_EXP |
| GSM3910593 |
CHO cells, A1-1_STA |
| GSM3910594 |
CHO cells, A1-2_STA |
| GSM3910595 |
CHO cells, A1-3_STA |
| GSM3910596 |
CHO cells, NDST-1_EXP |
| GSM3910597 |
CHO cells, NDST-2_EXP |
| GSM3910598 |
CHO cells, NDST-3_EXP |
| GSM3910599 |
CHO cells, NDST-1_STA |
| GSM3910600 |
CHO cells, NDST-2_STA |
| GSM3910601 |
CHO cells, NDST-3_STA |
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| Relations |
| BioProject |
PRJNA551666 |
| SRA |
SRP212617 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE133511_counts.csv.gz |
849.6 Kb |
(ftp)(http) |
CSV |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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