|
Status |
Public on May 21, 2020 |
Title |
High-throughput sequencing of circRNAs in ovarian cancer SKOV3 cell line |
Organism |
Homo sapiens |
Experiment type |
Non-coding RNA profiling by high throughput sequencing
|
Summary |
Circular RNAs(circRNAs) are conservative and stable and have been extensively studied in cancer in recent years. Expression profile of circRNA is largely unknown in ovarian cancer. This study explored circRNAs in the ovarian cancer cell line SKOV3.
|
|
|
Overall design |
We injected untreated SKOV3 ovarian cancer cells into nude mice peritoneal cavity to mimic the circRNAs formation and degradation during tumor cell growth. Tumor tissues with good growth were obtained from nude mice, and high-throughput sequencing was performed to obtain circRNAs stably expressed in all samples.
|
|
|
Contributor(s) |
Tang J, Chen L, Deng G |
Citation(s) |
32467669 |
Submission date |
Jul 02, 2019 |
Last update date |
Jun 01, 2020 |
Contact name |
Guanming Deng |
E-mail(s) |
dgm1993@126.com
|
Organization name |
Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University
|
Department |
Gynecologic Oncology
|
Street address |
283 Tongzipo Road, Yuelu District
|
City |
Changsha |
State/province |
Hunan |
ZIP/Postal code |
410013 |
Country |
China |
|
|
Platforms (1) |
|
Samples (3) |
|
Relations |
BioProject |
PRJNA552216 |
SRA |
SRP212747 |