|
| Status |
Public on Dec 05, 2019 |
| Title |
Single cell ATAC sequencing profile of quiescent mesenchymal progenitors |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
After tissue injury mesenchymal progenitor subsets undergo a transient proliferative expansion, morphological transition and migration from their perivascular niche. Some of these subsets contribute enduring populations to connective tissue structures adjacent to muscle. To gain insights into gene accessibility to complement the single cell RNA seq expression data previously obtained and to uncover the lineage potential of MPs in this context, tdTomato positive cells were profiled by single cell ATAC sequencing.
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| |
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| Overall design |
Single cell ATAC-seq analyses of enriched quiescent mesenchymal progenitors from skeletal muscle.
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| |
|
| Contributor(s) |
Scott RW, Underhill TM |
| Citation(s) |
31809738 |
| |
| Submission date |
Jul 11, 2019 |
| Last update date |
Feb 19, 2020 |
| Contact name |
Tully Michael Underhill |
| E-mail(s) |
tunderhi@brc.ubc.ca
|
| Phone |
604-822-5833
|
| Organization name |
University of British Columbia
|
| Department |
Biomedical Research Centre
|
| Street address |
2222 Health Sciences Mall
|
| City |
Vancouver |
| State/province |
British Columbia |
| ZIP/Postal code |
V6T 1Z3 |
| Country |
Canada |
| |
|
| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (1) |
| GSM3938397 |
Single cell ATAC-seq tdTomato MPs quiescent |
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| This SubSeries is part of SuperSeries: |
| GSE110038 |
Hic1 defines quiescent mesenchymal progenitor subpopulations with distinct functions and fates in skeletal muscle regeneration |
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| Relations |
| BioProject |
PRJNA554142 |
| SRA |
SRP214326 |
