|
| Status |
Public on Jul 16, 2019 |
| Title |
Natural killer cells suppress T cell tumor immune evasion [B16-F10 CRISPR/Cas9 NK cell screen] |
| Organism |
Mus musculus |
| Experiment type |
Other
|
| Summary |
Investigation of tumor genes which limit sensitivity to killing by NK cells through a genome-wide in vitro CRISPR/Cas9 screen
|
| |
|
| Overall design |
B16-F10 Cas9 expressing cells transduced with a genome-wide CRISPR library were successively co-cultured overnight with activated NK cells at an equal ratio. Experiment was performed in technical duplicate. An untreated control cultured alongside was used for comparison
|
| |
|
| Contributor(s) |
Freeman AJ, Kelly MJ, Kearney CJ, Oliaro J |
| Citation(s) |
31509742 |
| |
| Submission date |
Jul 15, 2019 |
| Last update date |
Sep 13, 2019 |
| Contact name |
Madison Kelly |
| E-mail(s) |
mjk4002@med.cornell.edu
|
| Organization name |
Weill Cornell Medicine
|
| Street address |
413 E69th Street
|
| City |
New York |
| State/province |
NY |
| ZIP/Postal code |
10021 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (3) |
|
| This SubSeries is part of SuperSeries: |
| GSE134265 |
Natural killer cells suppress T cell tumor immune evasion |
|
| Relations |
| BioProject |
PRJNA554591 |
| SRA |
SRP214593 |
