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| Status |
Public on Nov 02, 2021 |
| Title |
Gene expression analysis in HLHS iPSCs, iPSC-derived cardiac progenitors and cardiomyocytes |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
In the present study, genome-wide expression profiling (RNA-Seq) was carried out to identify genes dysregulated during cardiac differentiation of HLHS iPSCs.
Transcriptional profiling by RNASeq of three control and three HLHS iPSC lines was performed at various times during differentiation towards cardiac progenitors (CPCs) at D0, D1, D2, D3 and towards cardiomyocytes (CMs) at D6, D8, D14.
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| Overall design |
RNA from three control and HLHS iPSC lines differentiated into CPCs and CMs in three independent differentiation experiments in triplicates was isolated at D0, D1, D2, D3, D6, D8 and D14, pooled and subjected to RNA-Seq.
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| Contributor(s) |
Santamaria G, Moretti A |
| Citation(s) |
34694888 |
| |
| Submission date |
Aug 05, 2019 |
| Last update date |
Nov 03, 2021 |
| Contact name |
Gianluca Santamaria |
| E-mail(s) |
santamariagianluca@tum.de
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| Organization name |
Klinikum rechts der Isar – Technical University Munich
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| Department |
Department of Medicine I
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| Lab |
Molecular Cardiology
|
| Street address |
Ismaninger Strasse 22
|
| City |
Munich |
| State/province |
Germany |
| ZIP/Postal code |
81675 |
| Country |
Germany |
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| Platforms (1) |
| GPL15456 |
Illumina HiScanSQ (Homo sapiens) |
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| Samples (45)
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| Relations |
| BioProject |
PRJNA558778 |
| SRA |
SRP217509 |
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