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| Status |
Public on Oct 27, 2009 |
| Title |
Comparison of gene expression in melanoma of wild-type and VAP-1 -/- mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Vascular adhesion protein-1 (VAP-1) is an endothelial cell-surface protein. It is also an enzyme posessing semicarbazide-sensitive amine oxidase activity (EC.1.4.3.6). VAP-1 is involved in leukocyte traffic. To study the role of VAP-1 in tumor immunity, we compared gene expression profiles in melanomas growing in VAP-1 -/- mice and their wid-type littermates.
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| Overall design |
The B16-F10-Luc-G5 melanoma cells (Xenogen) were injected subcutaneously into abdominal area of 2 wild-type and 2 VAP-1 -/- mice. Tumors were grown until day 10 when mice were euthanized. Tumors were dissected and total RNA was isolated using the Qiagen RNA extraction kit.
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| Contributor(s) |
Marttila-Ichihara F, Auvinen K, Jalkanen S, Salmi M |
| Citation(s) |
19789345 |
| Submission date |
Nov 17, 2008 |
| Last update date |
Jan 18, 2013 |
| Contact name |
Kaisa Auvinen |
| E-mail(s) |
kakoski@utu.fi
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| Organization name |
University of Turku
|
| Department |
Medicity Research Laboratory
|
| Street address |
Tykistökatu 6
|
| City |
Turku |
| ZIP/Postal code |
20520 |
| Country |
Finland |
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| Platforms (1) |
| GPL6105 |
Illumina mouse-6 v1.1 expression beadchip |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA110657 |
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