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Status |
Public on Sep 04, 2019 |
Title |
Experimental evolution identifies adaptive aneuploidy as a mechanism of fluconazole resistance in Candida auris |
Organism |
[Candida] auris |
Experiment type |
Expression profiling by high throughput sequencing
|
Summary |
In the current study, we set out to explore the developmental mechanism of antifungal resistance in this fungus using an in vitro experimental evolution strategy.
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|
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Overall design |
total RNA profiles of drug resistant and sensitive strains of Candida auris
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|
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Contributor(s) |
Huang G, Bing J |
Citation(s) |
33077664 |
Submission date |
Sep 03, 2019 |
Last update date |
Jan 02, 2024 |
Contact name |
Jian Bing |
E-mail(s) |
bingj@fudan.edu.cn
|
Organization name |
Fudan University
|
Department |
School of Life Sciences
|
Street address |
Songhu Road, Yangpu District
|
City |
Shanghai |
ZIP/Postal code |
200438 |
Country |
China |
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Platforms (1) |
GPL27415 |
Illumina HiSeq 2000 ([Candida] auris) |
|
Samples (6)
|
GSM4057610 |
fluconazole sensitive Candida auris strain_1 |
GSM4057611 |
fluconazole sensitive Candida auris strain_2 |
GSM4057612 |
fluconazole sensitive Candida auris strain_3 |
GSM4057613 |
fluconazole resistant Candida auris strain_1 |
GSM4057614 |
fluconazole resistant Candida auris strain_2 |
GSM4057615 |
fluconazole resistant Candida auris strain_3 |
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Relations |
BioProject |
PRJNA563631 |
SRA |
SRP220132 |