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Status |
Public on Oct 21, 2022 |
Title |
Hepatic BCL6 and plasma triglycerides regulate sexual dimorphism in tissue tolerance [set 5] |
Organism |
Mus musculus |
Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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Summary |
Tissue tolerance is a sexually dimorphic trait. Here, we investigated the role of BCL6 in establishing hepatic chromatin landscape promoting sexually dimorphic tissue tolerance during E.Coli infection.
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Overall design |
Investigated the H3K27 acetylation in livers of Bcl6Flox/Flox and Bcl6Flox/Flox,Alb-Cre male and female mice infected with E.Coli and housed at +30ÂșC.
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Contributor(s) |
Nikkanen J, Leong YA, Chawla A |
Citation(s) |
36264814 |
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Submission date |
Oct 03, 2019 |
Last update date |
Feb 07, 2023 |
Contact name |
Joni Nikkanen |
E-mail(s) |
jonikkan@gmail.com
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Organization name |
UCSF
|
Street address |
555 Mission Bay Blvd S
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City |
San Francisco |
ZIP/Postal code |
94158 |
Country |
USA |
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Platforms (1) |
GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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Samples (23)
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This SubSeries is part of SuperSeries: |
GSE138396 |
An evolutionary trade-off between host immunity and metabolism drives fatty liver in male mice. |
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Relations |
BioProject |
PRJNA575718 |