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Series GSE138748 Query DataSets for GSE138748
Status Public on Dec 10, 2019
Title Transcriptome data from human endocrine cells recovered from mouse grafts with pre-engraftment controls
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We examined the transcriptomes of alpha and beta cells recovered from mouse sub-renal capsule grafts of human islets as compared to alpha and beta cells from the same islet preps pre-engraftment. We found that after three to four weeks in the graft the human islets were still glucose responsive, secreting insulin following glucose challenge. In addition, gene expression was largely unchanged from the pre-engraftment control samples.
 
Overall design Bulk and single-cell RNA-Seq analysis of human endocrine cells recovered from mouse engraftment
Web link https://doi.org/10.1096/fj.201901022RR
 
Contributor(s) Redick SD, Leehy L, Rittenhouse AR, Blodgett DM, Derr AG, Kucukural A, Garber MG, Shultz LD, Greiner DL, Wang JP, Harlan DM, Bortell R, Jurczyk A
Citation(s) 31914605
Submission date Oct 11, 2019
Last update date Jan 13, 2020
Contact name Alan G Derr
E-mail(s) alan.derr@umassmed.edu
Organization name University of Massachusetts Medical School
Department Program in Bioinformatics and Integrative Biology
Lab Garber Lab
Street address 55 Lake Ave North
City Worcester
State/province Massachusetts
ZIP/Postal code 01655
Country USA
 
Platforms (1)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (15)
GSM4118623 15275_alpha_pre
GSM4118624 15275_alpha_rec
GSM4118625 15275_beta_pre
Relations
BioProject PRJNA577039
SRA SRP225174

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE138748_RAW.tar 12.0 Mb (http)(custom) TAR (of TXT, XLSX)
GSE138748_Well_FACS_Status.txt.gz 2.8 Kb (ftp)(http) TXT
GSE138748_plateBarcodeMap.txt.gz 1.7 Kb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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