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| Status |
Public on Oct 18, 2022 |
| Title |
RNA-Seq Transcriptomic analysis in tumor and non-tumor tissues of Atg7-/- and Atg7-/-/Hmgb1-/- livers |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
HMGB1 is important for tumor development of autophagy-deficient liver. However, detailed molecular signals impacted by HMGB1 is unclear. RNA seq data will provide a comprehensive gene expression profile data that will help to dissect the signaling pathways affected by HMGB1 during tumorigenesis in autophagy deficient liver.
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| Overall design |
3 samples per group, total 12 samples, from 4 different groups of 15 month old mouse- Atg7-/- Tumor,Atg7-/- non-Tumor, Atg7-/-/Hmgb1-/- tumor, and Atg7-/-/Hmgb1-/- non-tumor
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| Contributor(s) |
Yin X, Khambu B |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Oct 21, 2019 |
| Last update date |
Oct 18, 2022 |
| Contact name |
Xiao-Ming Yin |
| Organization name |
Indiana University
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| Department |
Pathology and Laboratory Medicine
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| Street address |
975 W Walnut St IB411/406
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| City |
Indianapolis |
| State/province |
IN |
| ZIP/Postal code |
46202 |
| Country |
USA |
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| Platforms (1) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA578666 |
| SRA |
SRP226432 |
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