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Series GSE139570 Query DataSets for GSE139570
Status Public on Nov 07, 2019
Title Comparative analysis of squamate brains unveils multi-level variation in cerebellar architecture associated with locomotor specialization
Organisms Python regius; Eryx colubrinus; Pantherophis guttatus; Pogona vitticeps; Trioceros jacksonii; Basiliscus vittatus; Pseudopus apodus; Dasypeltis gansi; Chrysopelea ornata; Mochlus fernandi
Experiment type Expression profiling by high throughput sequencing
Other
Summary We exploited the extraordinary  ecomorphological diversity of squamates to assess  brain phenotypic diversification with respect to locomotor specialization, by integrating transcriptomic data along with other methods. We reveal significant changes in cerebellar morphology as well as dynamic gene expression that all correlate with locomotor behaviours.
 
Overall design RNA sequencing of adult cerebellum tissues from ten different squamate species, using NextSeq 500 platform (Illumina, U.S.A.).
Conclusions is only based on the 630 orthologous genes (present in the current table) identified among all ten species analyzed. We have not used all genes in our work, but only orthologous genes.
 
Contributor(s) Macrì S, Savriama Y, Khan I, Di-Poï N
Citation(s) 31804475
Submission date Oct 29, 2019
Last update date Dec 17, 2019
Contact name Nicolas Di-Poi
E-mail(s) nicolas.di-poi@helsinki.fi
Organization name University of Helsinki
Department Institute of Biotechnology, Helsinki Institute of Life Sciences
Street address Viikinkaari 1
City University of Helsinki
ZIP/Postal code 00014
Country Finland
 
Platforms (10)
GPL27693 Illumina NextSeq 500 (Basiliscus vittatus)
GPL27694 Illumina NextSeq 500 (Chrysopelea ornata)
GPL27695 Illumina NextSeq 500 (Dasypeltis gansi)
Samples (10)
GSM4143855 RNA seq species 1
GSM4143856 RNA seq species 2
GSM4143857 RNA seq species 3
Relations
BioProject PRJNA580270
SRA SRP227378

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE139570_FPKM_values.xlsx 72.6 Kb (ftp)(http) XLSX
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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