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Status |
Public on Nov 07, 2019 |
Title |
Comparative analysis of squamate brains unveils multi-level variation in cerebellar architecture associated with locomotor specialization |
Organisms |
Python regius; Eryx colubrinus; Pantherophis guttatus; Pogona vitticeps; Trioceros jacksonii; Basiliscus vittatus; Pseudopus apodus; Dasypeltis gansi; Chrysopelea ornata; Mochlus fernandi |
Experiment type |
Expression profiling by high throughput sequencing Other
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Summary |
We exploited the extraordinary ecomorphological diversity of squamates to assess brain phenotypic diversification with respect to locomotor specialization, by integrating transcriptomic data along with other methods. We reveal significant changes in cerebellar morphology as well as dynamic gene expression that all correlate with locomotor behaviours.
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Overall design |
RNA sequencing of adult cerebellum tissues from ten different squamate species, using NextSeq 500 platform (Illumina, U.S.A.). Conclusions is only based on the 630 orthologous genes (present in the current table) identified among all ten species analyzed. We have not used all genes in our work, but only orthologous genes.
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Contributor(s) |
Macrì S, Savriama Y, Khan I, Di-Poï N |
Citation(s) |
31804475 |
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Submission date |
Oct 29, 2019 |
Last update date |
Dec 17, 2019 |
Contact name |
Nicolas Di-Poi |
E-mail(s) |
nicolas.di-poi@helsinki.fi
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Organization name |
University of Helsinki
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Department |
Institute of Biotechnology, Helsinki Institute of Life Sciences
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Street address |
Viikinkaari 1
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City |
University of Helsinki |
ZIP/Postal code |
00014 |
Country |
Finland |
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Platforms (10)
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GPL27693 |
Illumina NextSeq 500 (Basiliscus vittatus) |
GPL27694 |
Illumina NextSeq 500 (Chrysopelea ornata) |
GPL27695 |
Illumina NextSeq 500 (Dasypeltis gansi) |
GPL27696 |
Illumina NextSeq 500 (Eryx colubrinus) |
GPL27697 |
Illumina NextSeq 500 (Lepidothyris fernandi) |
GPL27698 |
Illumina NextSeq 500 (Pantherophis guttatus) |
GPL27699 |
Illumina NextSeq 500 (Pogona vitticeps) |
GPL27700 |
Illumina NextSeq 500 (Pseudopus apodus) |
GPL27701 |
Illumina NextSeq 500 (Python regius) |
GPL27702 |
Illumina NextSeq 500 (Trioceros jacksonii) |
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Samples (10)
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Relations |
BioProject |
PRJNA580270 |
SRA |
SRP227378 |