|
| Status |
Public on Jun 28, 2021 |
| Title |
RNA-seq dataset for MPNST patient tissue samples |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Comprehensive transcriptomic profiling of PRC2 mutant MPNST patient tissues with adjacent normal tissues and neurofibroma patient tissues was performed to investigate gain of specific transcriptional signature associated with PRC2 loss during transformation to MPNST.
|
| |
|
| Overall design |
There are 17 samples with 7 tumor samples, 7 adjacent normal samples and 3 neurofibroma samples.
|
| |
|
| Contributor(s) |
Kochat V, Raman AT, Landers S, Bhalla A, Torres KE, Rai K |
| Citation(s) |
34283254 |
| |
| Submission date |
Dec 04, 2019 |
| Last update date |
Jul 22, 2021 |
| Contact name |
Ayush T Raman |
| E-mail(s) |
aayushraman09@gmail.com
|
| Organization name |
Broad Institute of MIT and Harvard
|
| Department |
Epigenomics Program
|
| Street address |
75 Ames St
|
| City |
Cambridge |
| State/province |
MA |
| ZIP/Postal code |
02142 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
|
| Samples (17)
|
|
| This SubSeries is part of SuperSeries: |
| GSE141439 |
Epigenomic reprogramming due to PRC2 functional loss induces an aggressive de-differentiated neural crest-like phenotype in MPNST |
|
| Relations |
| BioProject |
PRJNA593503 |
| SRA |
SRP234699 |
Less...
More...