|
| Status |
Public on Jan 13, 2020 |
| Title |
RNA sequencing from the microglia of mice with acute GvHD against syngeneic bone marrow transplanted and untreated controls |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Understanding the role of myeloid cells in GvHD of CNS. Microglia are the major immune cells of the CNS. We intend to understand if microglia play a role in GvHD of the CNS.
|
| |
|
| Overall design |
In order to study this, mice were lethally irradiated and transplanted with either syngeneic or allogeneic bone marrow and T cells. We isolated RNA from sorted microglia cells of the brain on day14 after transplantation to understand the molecular changes occurring within microglia. Four mice were analyzed per group
|
| |
|
| Contributor(s) |
Vinnakota JM, Zeiser R, Andrieux G, Boerries M |
| Citation(s) |
31846439 |
| Submission date |
Dec 09, 2019 |
| Last update date |
Oct 19, 2023 |
| Contact name |
Geoffroy Andrieux |
| Organization name |
University clinics Freiburg
|
| Street address |
Breisacherstr 153
|
| City |
Freiburg |
| ZIP/Postal code |
79110 |
| Country |
Germany |
| |
|
| Platforms (1) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA594334 |
| SRA |
SRP235261 |
Less...
More...