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Series GSE142819 Query DataSets for GSE142819
Status Public on Jul 01, 2021
Title Expression profile of plasma exosomal microRNAs in women with polycystic ovary syndrome and control women
Organism Homo sapiens
Experiment type Non-coding RNA profiling by high throughput sequencing
Summary Polycystic ovary syndrome (PCOS) is a highly prevalent endocrine-metabolic disorder. Epigenetic etiology is suggested to play an important role in PCOS pathogenesis, since it is hard to elucidate completely by genetic variations. Exosomal microRNAs (miRNAs) have recently been identified as a novel mechanism of intercellular communication, and a more stable regulator of gene expression compared with free miRNAs. The aim of this study is to detect the different expression profile of plasma exosomal miRNAs between PCOS patients and healthy controls.
 
Overall design Plasma exosomal miRNA profiles from 15 PCOS women and 15 control women. All participants were recruited in Center for Reproductive Medicine, Shandong University, from January to June in 2017.
 
Contributor(s) Jiang X, Cui L
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Jan 01, 2020
Last update date Jul 01, 2021
Contact name Xiao Jiang
E-mail(s) jx494329398@gmail.com
Organization name Center for Reproductive Medicine, Shandong University
Street address 157 Jingliu Road
City Jinan
ZIP/Postal code 250021
Country China
 
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (30)
GSM4240583 ExoC1-miRNA
GSM4240584 ExoC2-miRNA
GSM4240585 ExoC3-miRNA
Relations
BioProject PRJNA598459
SRA SRP239237

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE142819_processed_data.xlsx 368.3 Kb (ftp)(http) XLSX
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Raw data are available in SRA
Processed data are available on Series record

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