|
Status |
Public on Mar 25, 2020 |
Title |
RNA-seq transcriptome profiling of C. elegans mutants defective in IL-17 signaling |
Organism |
Caenorhabditis elegans |
Experiment type |
Expression profiling by high throughput sequencing
|
Summary |
The whole-animal transcriptomes of ilc-17.1, malt-1 and nfki-1 mutants comapared to that of controls reveals a transcriptional fingerprint of C. elegans IL-17 signaling.
|
|
|
Overall design |
Whole-animal RNA-Seq profiles of malt-1; npr-1, ilc-17.1; npr-1, and nfki-1; npr-1 double mutants were compared to that of npr-1 controls.
|
|
|
Contributor(s) |
Flynn S, Crisp A, de Bono M |
Citation(s) |
- Flynn SM, Chen C, Artan M, Barratt S et al. MALT-1 mediates IL-17 neural signaling to regulate C. elegans behavior, immunity and longevity. Nat Commun 2020 Apr 29;11(1):2099. PMID: 32350248
|
|
Submission date |
Jan 22, 2020 |
Last update date |
May 12, 2020 |
Contact name |
Alastair Crisp |
Organization name |
MRC Laboratory of Molecular Biology
|
Street address |
Francis Crick Avenue
|
City |
Cambridge |
ZIP/Postal code |
CB2 0QH |
Country |
United Kingdom |
|
|
Platforms (1) |
GPL22765 |
Illumina HiSeq 4000 (Caenorhabditis elegans) |
|
Samples (72)
|
|
Relations |
BioProject |
PRJNA602662 |
SRA |
SRP243896 |