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Series GSE145638 Query DataSets for GSE145638
Status Public on Apr 17, 2020
Title Transcriptome dynamics of hematopoietic stem cell formation revealed using a combinatorial Runx1/Ly6a reporter system
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Single cell RNA-Seq time-course analysis revealed that as pre-HSCs mature into fetal liver-stage HSCs they show signs of interferon exposure, multi-lineage differentiation gene expression signatures, and prolonged cell cycle reminiscent of quiescent adult HSCs.
 
Overall design Investigation of transcriptome dynamics of hematopoietic stem cell formation using a combinatorial Runx1/Ly6a reporter system
 
Contributor(s) Chen M, da Rocha EL, Cahan P, Hunter P, Sousa P, Kubaczka C, Mullin N, Fujiwara Y, Nguyen M, Landry S, Han A, Yang S, Tan Y, Lu Y, Jha D, Vo LT, Zhou Y, North TE, Zon LI, Daley GQ, Schlaege TM
Citation(s) 32302558
Submission date Feb 20, 2020
Last update date May 19, 2020
Contact name Yuqi Tan
Organization name Johns Hopkins University
Street address 733 North Broadway, MRB 653
City Baltimore
State/province MD
ZIP/Postal code 21205
Country USA
 
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (127)
GSM4322566 single cell from AUV [LIB019717_GEN00050442_S1_R1]
GSM4322567 single cell from AUV [LIB019717_GEN00050443_S2_R1]
GSM4322568 single cell from AUV [LIB019717_GEN00050444_S3_R1]
Relations
BioProject PRJNA607786
SRA SRP250162

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE145638_counts_matrix.csv.gz 4.2 Mb (ftp)(http) CSV
GSE145638_sample_table.csv.gz 4.4 Kb (ftp)(http) CSV
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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