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| Status |
Public on Jan 29, 2009 |
| Title |
MicroRNA expression from bronchial epithelial cell samples of current and never smokers. |
| Platform organisms |
Caenorhabditis elegans; Drosophila melanogaster; Danio rerio; Homo sapiens; Mus musculus; Rattus norvegicus |
| Sample organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
|
| Summary |
MicroRNA expression was assayed from bronchial epithelial cells collected via bronchoscopy from healthy current and never smoker volunteers in order to determine the effect of cigarette smoke exposure on airway epithelial microRNA expression
Keywords: Global microRNA expression profiling
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| Overall design |
Bronchial epithelial cells were collected from current and never smokers via bronchoscopy. Low molecular weight RNA ( < 200 nucleotides) was isolated and hybridized to Invitrogen NCode microRNA microarrays to determine which microRNAs detected in bronchial epithelial cells were differentially expressed in the airways of smokers.
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| |
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| Contributor(s) |
Sridhar S, Spira A |
| Citation(s) |
19168627 |
| |
| Submission date |
Jan 29, 2009 |
| Last update date |
Mar 20, 2012 |
| Contact name |
Sriram Sridhar |
| E-mail(s) |
sridhars@medimmune.com
|
| Phone |
6178771485
|
| Organization name |
MedImmune
|
| Department |
Translational Medicine
|
| Street address |
1 MedImmune Way
|
| City |
Gaithersburg |
| State/province |
MD |
| ZIP/Postal code |
20878 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL8131 |
Invitrogen NCode Multi-Species miRBase Microarray V2 |
|
| Samples (22)
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| This SubSeries is part of SuperSeries: |
| GSE14224 |
MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium |
|
| Relations |
| BioProject |
PRJNA114429 |
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