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| Status |
Public on Mar 10, 2020 |
| Title |
RNA Sequencing Facilitates Quantitative Analysis of Wild Type and FAK-/- Wnt1 driven mammary tumor cell transcriptomes |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We examined FAK deletion induced changes in various cellular processes and signalling pathways in an unbiased manner by transcriptomic analysis
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| |
|
| Overall design |
Tumor cells were isolated from MMTV-Wnt1 Fak flox/flox mice. Tumor cells were then transduced with Cre-ERT and deletion of FAK was induced by treating with 100 nM OHT for 3days. RNA was isolated from untreated cells serving as controls and treated cells with FAK deletion and subjected to RNA sequencing.
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| |
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| Contributor(s) |
Ritama P, Guan J, Kok YS |
| Citation(s) |
32493400 |
| |
| Submission date |
Mar 09, 2020 |
| Last update date |
Jun 09, 2020 |
| Contact name |
Jun lin Guan |
| E-mail(s) |
guanjl@ucmail.uc.edu
|
| Organization name |
University of Cincinnati
|
| Department |
Cancer Biology
|
| Lab |
Jun lin Guan
|
| Street address |
3125 Eden Ave
|
| City |
Cincinnati |
| State/province |
Ohio |
| ZIP/Postal code |
45219 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL15103 |
Illumina HiSeq 1000 (Mus musculus) |
|
| Samples (6)
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| Relations |
| BioProject |
PRJNA611592 |
| SRA |
SRP252088 |
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