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| Status |
Public on May 27, 2020 |
| Title |
Chromatin state maintains human myeloid leukemia by regulating m6A demethylase ALKBH5 expression [Slam-seq] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
ALKBH5 is the RNA N(6)-methyladenosine (m6A) demethylase. To understhand the function and mechnism of ALKBH5 in human acute myeloid leukemia, we compared the RNA decay rate in wild-type and ALKBH5-knock-down THP1 cells.
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| |
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| Overall design |
SLAM-seq in wild-type or ALKBH5 knock-down THP1 cells
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| |
|
| Contributor(s) |
Wang J, Li Y, Wang P, Han G, Zhang H |
| Citation(s) |
32402251 |
| Submission date |
Mar 12, 2020 |
| Last update date |
May 27, 2020 |
| Contact name |
Jiazhen Wang |
| E-mail(s) |
jiazhen_wang@hactcm.edu.cn
|
| Organization name |
Henan University of Chinese Medicine
|
| Street address |
156 Jinshui East Road
|
| City |
Zhengzhou |
| ZIP/Postal code |
450046 |
| Country |
China |
| |
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| Platforms (1) |
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| Samples (16)
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| This SubSeries is part of SuperSeries: |
| GSE128575 |
Chromatin state maintains human myeloid leukemia by regulating m6A demethylase ALKBH5 expression |
|
| Relations |
| BioProject |
PRJNA612248 |
| SRA |
SRP252559 |
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