|
| Status |
Public on Jun 30, 2020 |
| Title |
Quantitative translation of dog-to-human aging by conserved remodeling of the DNA methylome |
| Organism |
Canis lupus familiaris |
| Experiment type |
Methylation profiling by high throughput sequencing
|
| Summary |
We generated sequencing data for 104 dogs using targeted-bisulfite sequencing with targets selected to the human 450K methylation array. Using these data, we identify a conserved methylation signature that can be used to quantitatively translate dog years to human years and also extends to mice.
|
| |
|
| Overall design |
Targetted bisulfite-sequencing of 104 dogs with DNA obtained from blood
|
| |
|
| Contributor(s) |
Wang T, Ideker T |
| Citation(s) |
32619550 |
| |
| Submission date |
Mar 13, 2020 |
| Last update date |
Sep 29, 2020 |
| Contact name |
Tina Wang |
| Organization name |
University of California, San Diego
|
| Street address |
9500 Gilman Dr
|
| City |
La Jolla |
| State/province |
CA |
| ZIP/Postal code |
92037 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24229 |
Illumina HiSeq 4000 (Canis lupus familiaris) |
|
| Samples (109)
|
|
| Relations |
| BioProject |
PRJNA612432 |
| SRA |
SRP252679 |
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